The Luxembourg Institute of Health (LIH) is the leading public research center in Luxembourg for basic, pre-clinical and clinical research in biomedicine and public health. Our clinically-oriented biomedical research activities in Oncology, Infection & Immunity and Population Health encompass the generation of knowledge on the pathogenesis, diagnosis and treatment of diseases with large impacts on public health and the epidemiological surveillance of these diseases. With the mission to deliver scientific, economic and societal value for Luxembourg, LIH aims to translate knowledge into clinical applications impacting on healthcare systems while shaping personalized medicine.
2-year fixed-term contract, full time. Start date: mid 2021
Background. Obesity is a public health concern worldwide due to the rising prevalence and associated health conditions, including in particular cardiometabolic comorbidities. In most published studies, oxidative stress (OS) increase and low antioxidant status (AS) were highlighted as emerging risk factors of developing obesity related morbi-mortality. Nevertheless, recent evidence suggested that obesity might not necessarily be associated with any cardiometabolic health issue. Contrarily, having a normal weight does not guarantee a good cardiometabolic health. This emphasizes the importance of understanding the mechanisms behind the development of the metabolic abnormalities for each weight category.
Objectives. The aim of the project is: 1.) to investigate the relationship between metabolic abnormalities, oxidative stress increase and low antioxidant status, independently of the weight status, and 2.) to provide easy-to-use tools to assess these emerging risk factors (OS, AS), as they are currently lacking.
Training and research environment. The Nurition and Health (NutriHealth) Research Group is a dynamic and multinational team belonging to the Department of Population Health. The Nutrition and Health Research Team works at the intersection of basic research and nutritional epidemiology with a focus on translational aspects to improve population health.
The Post-doctoral Fellow will be in charge of a Marie Skłodowska-Curie Action Individual Fellowships (MSCA IF) funded project that aims to investigate the relationship between metabolic abnormalities, oxidative stress increase and low antioxidant status, independently of the weight status.
Of note, the project proposal has to be further developed by the Post-Doc candidate in collaboration with the NutriHealth Team, from now on until mid-September 2020, when it should be submitted for MSCA IF funding. The work on the project might start in mid 2021 if funded.
In line with the mobility rule associated to the eligibility conditions of MSCA IF, the researcher must not have resided or carried out his/her main activity (work, studies, etc.) in Luxembourg for more than twelve months since September 2017.
This project will be co-supervised by Dr. Torsten Bohn (PI) & Dr. Hanen Samouda (PI).
Key Skills, Experience and Qualifications
• PhD with a background/education in nutrition, biochemistry, molecular chemistry or equivalent
• Solid skills in statistics
• Excellent time management, rigor, perseverance, scientific creativity and originality, writing skills, sense of priority and ability to work with others.
• Fluency in English is mandatory.
Researchers are supported by easy access to scientific expertise, well-equipped facilities, an active seminar program as well as the possibility for close collaborations with universities and other research institutes.
More information about the group can be found here: https://sites.lih.lu/nutrihealth-group/
Located in Luxembourg, the LIH offers the opportunity to work in a dynamic, international and multilingual
environment that values personal respect and professional achievement based on the highest intellectual and ethical standards. The job advertisement is also published on our website www.lih.lu/jobs.