We are looking for a highly motivated postdoctoral research associate to join the Cell Signaling and Tumorigenesis Laboratory (PI: Dr. James Robinson) at The Hormel Institute – University of Minnesota. The Cell Signaling and Tumorigenesis Laboratory focuses on the molecular mechanisms by which oncogenic signaling regulates tumorigenesis, with the ultimate goal of developing therapeutic approaches to eliminate cancer. The applicant will work on an American Cancer Society funded project to study resistance to targeted therapy in melanoma. They should hold a Ph.D. in biology or a related field and have a track record of publications in peer-reviewed journals. They must have strong organizational and timely record-keeping skills. They should have the ability to multi-task and perform work with a high degree of attention to detail and to troubleshoot and interpret data independently. Excellent written and oral communication skills are essential. Experience of genetic engineering using CRISPR-CAS9 is an absolute requirement for this position. The role is an excellent opportunity to learn a number of exciting, cutting-edge techniques in mouse modeling, molecular biology, genetic engineering, and proteomics. The ideal applicant is a problem solver with a positive attitude, excellent organizational, communication, and interpersonal skills.
Key Responsibilities: Genetic engineering cultured cells, creating and analyzing mouse models, validating interpreting data, and preparing manuscripts in English. The successful applicant will be strongly encouraged to apply for postdoctoral training grants.
Ph.D. in molecular biology or equivalent.
Genetic engineering using CRISPR/Cas9
Cell/tissue culture experience
Transfection, viral transduction, and/or electroporation of genetic material into cells.
Preparing manuscripts in English
Proficiency in both written and spoken English
Experience with mouse models.
Experience with RNA-Seq
Managing large datasets and/or databases
Microsoft Office (Word, Excel, and/or PowerPoint)
The Hormel Institute, a biomedical research center of the University of Minnesota, was established in 1942 and has an excellent reputation and long history for producing world-class medical research. The Institute’s research success has resulted in a second major expansion of its research facilities and includes an additional new state-of-the-art laboratory building that opened in January 2016. The Hormel Institute offers its research scientists complete access to state-of-the- art cutting edge equipment that includes a cryo-electron microscope (Titan Krios and Tecnai G2 Spirit Biotwin); FACS cell sorter; confocal microscopy; flow cytometry; protein crystallography robotics and defraction system; nano-HPLC-AB SCIEX triple TOF 5600 mass spectrometry; Leica tissue processor, embedder and microtome; real-time PCR instrumentation; 5 racks of Linux GPU supercomputers for computational biology and bioinformatics; spectrophotometers; and Western blot imagers.
* THE HORMEL INSTITUTE IS LOCATED IN AUSTIN, MN, APPROXIMATELY 35 MILES SOUTHWEST OF ROCHESTER, MN, AND APPROXIMATELY 100 MILES SOUTH OF MINNEAPOLIS/ST. PAUL.*
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