Howard Hughes Medical Institute (HHMI) is an independent, ever-evolving philanthropy that supports basic biomedical scientists and educators with the potential for transformative impact. We make long-term investments in people, not just projects, because we believe in the power of individuals to make breakthroughs over time. HHMI scientists have radically advanced the understanding of cells, the brain, the immune system, the development of organs, and how to treat many diseases. Founded in 1953 by aviator and industrialist Howard R. Hughes, HHMI is headquartered in Chevy Chase, Maryland, and employs more than 2,500 people across the U.S.
We are currently seeking a forward-thinking, inventive and results driven Postdoctoral Associate within the lab of Dr. Robert Lefkowitz at Duke University in Durham, NC. The Lefkowitz lab studies the molecular and regulatory properties of G protein-coupled receptors (GPCRs), also known as seven transmembrane spanning receptors (7TMRs). Current work in the lab focuses on understanding how GPCR cell signaling, by biased or unbiased ligands, is mediated through GPCRs and their transducers, the G proteins and β-arrestins. The lab utilizes techniques ranging from biophysics to pharmacology to cell biology to in vivo animal disease models – and more information on their research can be found on their website: http://www.lefkolab.org/home.html
We are targeting candidates who have a strong background in a variety of biochemical, biophysical, and cell biological techniques. The lab thrives on developing novel solutions to challenging problems – so we need someone who isn’t afraid to both think outside the box and challenge the status quo. We feel science moves forward best when you aren’t afraid to question everything and embrace creative experimental approaches – and we want team members who are as enthusiastic about that approach as they are about our science.
- within the last 2 years
- Background in structural biology strongly preferred
- Effective communication skills, self-motivated, and a strong work ethic
- Ability to work both independently and in a collaborative group environment
- Experience with either X-Ray Crystallography or Cryo-Electron Microscopy strong pluses
Applicants should submit both their curriculum vitae and a detailed statement on how their experience and interests relate to our work.