University of Gothenburg (GU)

Postdoctor in Molecular psychiatry

University of Gothenburg (GU)

Gothenburg, Sweden

Postdoctor in Molecular psychiatry

The University of Gothenburg tackles society’s challenges with diverse knowledge. 49 000 students and 6400 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract scientists and students from around the world. With new knowledge and new perspectives, the University contributes to a better future.

At the Institute of Neuroscience and Physiology, at the Sahlgrenska Academy, we conduct research and education covering a wide range of knowledge areas. The institute comprises five different departments: Clinical Neuroscience, Health and Rehabilitation, Pharmacology, Physiology and Psychiatry and Neurochemistry. The Institute of Neuroscience and Physiology, invites applications for a postdoctoral position at the Department of Psychiatry and Neurochemistry. This project will be conducted at the Department of Neurochemistry and Psychiatry which is a research-intensive workplace, including ample opportunities for interaction with other research groups within the field of psychiatry and molecular neurobiology.

Bipolar disorder is a serious mental illness with both individual suffering of the patient and large costs for the society. The disorder has a strong genetic background, with for instance risk alleles of the calcium channel gene CACNA1C involved. The research group is studying severe mental illness, primarily bipolar disorder, with both experimental and clinical register-based studies. This project focuses on how disturbed calcium signaling during neural development may lead to mental illness. We develop IPS (induced pluripotent stem) cell-based models of neural development from a number of bipolar patients and controls genotyped for CACNA1C. Visit www.smedlerlab.org for more information.

Subject area

Molecular psychiatry

Subject area description

Several processes, including genetic and activity dependent factors, control neural development and lay the foundation of those neural networks that control the function of the brain. Early neural networks exhibit spontaneous electrical activity, and thus also calcium signaling. Voltage-dependent calcium channels, including those encoded by CACNA1C, are essential for this activity.

Job assignments

The postdoc will be responsible for neural differentiation of IPS cells from several individuals. Besides cell culture work, this includes RNA sequencing, calcium imaging, immunocytochemistry and other various methods used to investigate the effect on neural development that both the disease and risk variants of CACNA1C have. In addition, the postdoc will be involved in preparation of manuscripts, supervision of master students and possibly also graduate students working on related projects. The postdoc is also expected to apply for own funding in addition to present grants.

Eligibility

To qualify as a postdoctoral researcher the applicant should hold a PhD in a relevant subject (such as molecular and cellular biology or neuroscience). Since postdoctoral constitutes a qualifying appointment for junior researchers, we aim to target those who have a doctoral degree not older than 3 years from the application deadline.

Assessment

In specific, the candidate should have extensive experience from cell and molecular biology, preferably within molecular neurobiology or stem cell biology. The candidate must demonstrate published articles in peer-review journals as first author. Good documentation skills as well as proficiency in both spoken and written English are required. The candidate(s) should be willing to work in a team to pursue his/her research. Personal suitability is of great importance when evaluating applicants.

Employment

The employment is limited (temporary) for 24 months, 100% of full-time, and is placed at the Institute of Neuroscience and Physiology. Starting date; as soon as possible or as agreed.

Appointment procedure

In order to apply for a position at the University of Gothenburg, you have to register an account in our online recruitment system.

For further information

If you have questions regarding the employment please contact Research leader Erik Smedler, phone; +4670 283 5159, e-mail; erik.smedler@gu.se Manager in charge is Professor/Head of Department Henrik Zetterberg, phone; +46 768 672 647, e-mail; henrik.zetterberg@clinchem.gu.se and Senior Lecturer/Assistant Head of Department Silke Kern, phone; +46 762 365 332, e-mail; silke.kern@neuro.gu.se Application documents are not to be submitted through the contact persons.

Unions

Union representatives at the University of Gothenburg: http://www.gu.se/english/about_the_university/jobopportunities/ union-representatives

Information for International Applicants

Choosing a career in a foreign country is a big step. Thus, to give you a general idea of what we and Gothenburg have to offer in terms of benefits and life in general for you and your family/spouse/partner please visit: https://www.gu.se/english/welcomeservices/staff https://www.movetogothenburg.com/

How to apply

In order to apply for a position at the University of Gothenburg, you have to register an account in our online recruitment system https://www.gu.se/en/about-the-university/work-at-the-university-of-gothenburg/vacancies

It is the responsibility of the applicant to ensure that the application is complete in accordance with the instructions in the job advertisement, and that it is submitted before the deadline. Please enclose PhD certificate with the application.

Closing date: 2021-03-08

The University of Gothenburg promotes equal opportunities, equality and diversity. Salary is determined on an individual basis. Applications will be destroyed or returned (upon request) two years after the decision of employment has become final. Applications from the employed and from those who appeal the decision will not be returned.

Please apply via recruiter’s website.

Quote Reference: PAR 2021/80