Postdoc in single-cell and spatially defined isoform analysis of health and disease

Weill Cornell Medicine (WCM), Cornell University

New York, United States

We have currently two postdoctoral positions available in our collaborative lab at WCMC (the Medical School of Cornell University) in New York City.

 

One position has a computational focus geared towards algorithm development and data analysis revolving around healthy and diseased brain using single-cell and spatial long-read sequencing. The perfect candidate would have a PhD degree in bioinformatics, computer science or similar as well as established coding experience in R/Matlab/Python or C++/Java.

 

The other position is a wet lab tech-dev position centered around single-cell and spatial long-read methods to further our understanding of the brain in neurodegeneration among others. The perfect candidate would have a PhD in biology, neuroscience or similar and a strong background in molecular biology and sequencing (e.g., single-cell technologies and/or long-read sequencing).

 

For both positions, tight collaboration across disciplines (informatics, neuroscience and molecular biology) is key in the lab and candidates should therefore like such a setting.

 

A few representative papers include:

a.     https://www.nature.com/articles/nbt.4259 (development of single-cell long-read seq using 10x + PacBio/Nanopore applied to early postnatal mouse brain)

b.     https://www.nature.com/articles/s41467-020-20343-5 (bioinformatic development of sample comparison using single-cell long-read sequencing and development of slide-isoform sequencing (Sl-ISO-Seq))

c.     https://www.nature.com/articles/nbt.3242 (wetlab and bioinformatic development of Illumina-based long-read sequencing applied to human and mouse adult brain)

d.     https://www.nature.com/articles/nbt.2705 (development of PacBio for transcriptomics … applied to transcriptome sequencing in multiple human organs)

 

We are located at Weill Cornell Medical College on Manhattan’s Upper East Side. The university has a nearby postdoc housing program for easier rental in New York City.

 

If you are interested, please send a CV and contact information for references to tilgnerlab@gmail.com.


"Diversity is one of Weill Cornell Medicine’s core values and is essential to achieving excellence in patient care, research, and education. We welcome applications from candidates who share our commitment to fostering a culture of fairness, equity, and belonging. Weill Cornell Medicine is an Equal Employment Opportunity Employer, providing equal employment opportunities to all qualified applicants without regard to race, sex, sexual orientation, gender identity, national origin, color, age, religion, protected veteran or disability status, or genetic information.”

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Postdoc in single-cell and spatially defined isoform analysis of health and disease