Leiden University Medical Center (LUMC)

Postdoc CRISPR/Cas9 Gene Editing of hiPS Cells

Leiden University Medical Center

Leiden, Netherlands

The position
The LUMC human iPSC hotel is looking for a highly motivated postdoctoral fellow to work on the genetic modification and differentiation of human induced pluripotent stem cells (hiPSCs). Are you the postdoc we are looking for?
As a postdoc you will be part of a team (the LUMC hiPSC hotel) that generates, differentiates and genetically modifies hiPSCs and that has a supportive role towards our customers. Your tasks will involve optimizing and designing gene editing strategies of hiPSCs for the generation of isogenic controls, reporters, knockouts and so on, as part of a service for our customers. This research will include working with state-of-the-art gene-modifying tools, reprogramming vector systems, etc. You will be expected to supervise personnel in coordination with the other team members on a daily basis, as well as organize and convey your expertise and experimental findings.

Your profile
We are looking for a highly motivated candidate who:
• has obtained a PhD degree in Biomedical sciences, Molecular Biology, Biochemistry or a similar field
• possesses solid experience in both molecular and cell biology
• is also experienced in genetic modification, from design to analysis
• preferably has additional experience with CRISPR/Cas9 and culturing of human iPSC
• can work both independently and in a team, and is service-minded

Our offer
You will be employed on the basis of a 36 hour work week. Appointment is for initially for one year possibly for the duration of the project, extension of three years. The salary will depend on your qualifications and experience, with a maximum of € 4,361 gross per month based on a full time position (scale 10 of the Collective Labor Agreement for University Hospitals).

Working at the LUMC
The LUMC is a center for medical innovation that aims to improve patient care through leading international research. So as to also provide our patients with a safe and friendly environment, we need doctors, medical care specialists, support staff and academic researchers. The LUMC hiPSC hotel was founded in 2011 and is a joint initiative of the Departments of Anatomy and Embryology (C. Mummery), and Cell and Chemical Biology (R. Hoeben). We are an international team of two postdoctoral fellows, three research technicians, and two daily supervisors. The main goal of the LUMC hiPSC hotel is to provide a state-of-the-art service for the generation, characterization, and genetic modification of hiPSCs. In addition, the LUMC hiPSC hotel guides streamlining of differentiation protocols for research groups within the LUMC. The LUMC focuses on medical innovation to improve patient care through leading international research.

More information
A detailed description of this position can be found on www.werkenbijhetlumc.nl. If you have any questions or would like more information about this position, please contact Mr. Dr. Christian Freund, Department of Anatomy & Embryology, telephone +31 (0)71 526 93 51.

How to apply
If you are interested in this position, please complete the application form by June the 1st, 2019 at the latest. You can also apply through the website www.lumc.nl/vacatures.

Link to application form: https://bit.ly/2GTd0UU

Please apply via recruiter’s website.

Quote Reference: D.19.MS.CV.09