PhD student in ferroptotic cell death research (f/m/d)

Helmholtz Zentrum München - German Research Center for Environmental Health (HMGU)

Neuherberg (bei München), Germany

Work group:

Institute of molecular Toxicology and Pharmacology

Area of research:

PHD Thesis

Starting date:


Contract time limit:


Job description:

As German Research Center for Environmental Health, Helmholtz Zentrum München pursues the goal of developing personalized medical approaches for the prevention and therapy of major common diseases such as diabetes mellitus, allergies and lung diseases. To achieve this, it investigates the interaction of genetics, environmental factors and lifestyle.

The Institute of Molecular Toxicology and Pharmacology (TOXI) investigates mechanisms by which the organism responds to physiological signals and foreign chemicals. The aim is to understand how these factors affect cellular signaling and genetic programs and the implications for the whole organism, including development and progression of chronic diseases such as cancer, autoimmune diseases and metabolic disorders. This knowledge enables the development of strategies for reducing health risks and innovative therapeutic approaches. It also supports the systematic drug discovery/development process of the centre.

At the “Assay Development and Screening Platform” you will find an interdisciplinary environment working on signaling processes as well as early drug discovery.

Our laboratory is interested in ferroptotic cell death as well as cellular signaling regulated by ubiquitination processes. Our main focus within this project is to uncover novel pathways and modulators of ferroptosis by cellular enzymes including ubiquitin enzymes.

We are now looking for a motivated

PhD student in ferroptotic cell death research (f/m/d)

Your mission

Identify novel cellular modulators of ferroptosis through focused siRNA and CRISPR library screeningsInvestigate the impact of a selection of characterized small molecule on ferroptosis regulation

Your qualifications

Diploma or MSc in Biology, Biochemistry of related life sciencesGood experience in cell biology and cell culture techniquesGood knowledge of current molecular biology and biochemical techniquesBasic knowledge in data science is highly desirableTeam player skills and enthusiasm to work in a multi-disciplinary, collaborative environment

What we offer you

A challenging and versatile field of work providing you with the freedom to follow your instinct and be creative. With the help of extensive and goal-orientated professional development measures and career-building programmes we encourage you to grow as a person. To ensure a good work/life balance we assist you with flexible working hours, in-house health management, a nursery, and an “Elder Care” concept as well as other consultation and support options.

Munich, with its numerous lakes and its vicinity to the Alps, is considered to be one of the cities with the best quality of life worldwide. With its first-class universities and research institutes it offers an intellectually stimulating environment.

Remuneration and benefits are in accordance with the collective agreement for the public service (EG 13 50% TV EntgO Bund). In addition, there is also the possibility of granting an allowance amounting to 15% if the necessary conditions are fulfilled.

The position is (initially) limited to three years.

The activity involves special knowledge and experience specific to own scientific skills.

Having been awarded the "Total E-Quality" seal we endorse a system of equal opportunities. Applications from women are especially welcome. Severely disabled candidates are given preference if they are of equal merit concerning the position in question.

Curious? If you have further questions, simply contact Dr. Kamyar Hadian on 089 3187-2664, who will be happy to be of assistance.

We are looking forward to receiving your comprehensive online application.

Please apply via recruiter’s website.

Quote Reference: 2019/0391