Flanders Institute for Biotechnology (VIB)

PhD positions (2) on lysosomal homeostasis in Alzheimer’s disease and Dementia with Lewy Bodies

Flanders Institute for Biotechnology (VIB)

Leuven, Belgium

The Laboratory for Membrane Trafficking, headed by Wim Annaert is part of the Department of Neurosciences  and of the VIB-KU Leuven Center for Brain & Disease Research (CBD) at KU Leuven/ Campus Gasthuisberg, focusing on different aspects of neuronal connectivity and synapse biology in the context of neurodevelopment and neurodegeneration. The VIB-CBD hosts 18 research groups with over 300 neuroscience researchers from almost 40 different nationalities.  

Our laboratory explores the basic molecular mechanisms underlying early stages of neurodegenerative diseases, with a particular focus on endo-lysosomal transport regulation related to risk genes implemented in late onset Alzheimer’s disease (project 1) and Dementia with Lewy Bodies (project 2). Our research combines biochemistry and molecular/cell biology methods in neuronal cultures (including from iPSCs) and in vivo (mice) systems. Herein, we apply state-of-the-art imaging including live super-resolution and single molecule localization microscopy.


We are looking for highly motivated PhD students with a keen interest in neurodegeneration and a strong commitment to basic research to join our team of researchers.

The candidate:

  • Should hold a Master degree with distinction in biomedical sciences, medicine or bio-engineering
  • Should be a team player with good communication and writing skills
  • Should have a good mastery of the English language
  • Experience in neuronal cell culture and/or in vivo mice models will be of added value.

Please note that you should be eligible to obtain a personal fellowship with the FWO


We offer

  • A fulltime 1-year contract extendable to 4 years to work in an enthusiastic and dynamic scientific environment.  
  • The VIB-Center for Brain & Disease (CBD) Research at KU Leuven provides ample opportunities to present and share data on weekly seminars, lectures and international conferences. 
  • Different state-of-the-art core facilities are available for all CBD researchers.

Starting date: September

How to apply?

For additional information, please contact Wim Annaert.

Applications should be submitted through the VIB HR application tool. Please complete the online application procedure and include a CV, a motivation letter, a summary of research experience (and publications if applicable) and the contact information of 2 referees, one being the mentor of your master thesis. The best-ranked candidates will be invited for an interview.

Profile and selected papers of the Annaert lab: http://www.vib.be/en/research/…

Further info on VIB-CBD:

Please apply via recruiter’s website.

Quote Reference: 27135