PhD Position in RNA Bioinformatics

Buchmann Institute for Molecular Life Sciences (BMLS), GU

Frankfurt, Hessen, Germany

The Buchmann Institut for Molecular Life Science offers a PhD position in RNA Bioinformatics (E13 TV-G-U, 65%) in the research group of Dr. Kathi Zarnack. The position is initially for three years, the expected starting date is 01.09.2019 or later.


The successful applicant will contribute to internationally competitive research on genomics approaches to study the link between pre-mRNA splicing, alternative polyadenylation and nuclear export in mouse. The aim is to dissect the molecular mechanisms that control these processes and to investigate the consequences of impaired regulation for the cells. The project is part of the CRC902 “Molecular Principles of RNA-based Regulation” in collaboration with JProf. Michaela Müller-McNicoll.


You will

·      Study the molecular mechanisms of posttranscriptional regulation at subsequent steps in RNA processing

·      Analyse and interpret genome-wide datasets to deduce complex functional interrelationships

·      Work in close collaboration with experimental researchers

·      Communicate with internal and external partners


Required qualifications

·      MSc in Bioinformatics, Systems Biology, Molecular Biology or related areas

·      Previous experience with high-throughput functional genomics data, such as RNA-seq, CLIP or ChIP-seq

·      Good programming skills

·      Familiarity with R is a plus

·      Good understanding of molecular biology


We offer

·      A stimulating, diverse and international research environment

·      Working as part of a young and motivated team

·      The possibility to work with first-hand state-of-the-art datasets


To apply, please email a cover letter stating your research interests, a motivation statement, your CV, certificates and contact addresses of two referees in a single PDF file to Dr. Kathi Zarnack ( until 28.06.2019.

The Goethe University Frankfurt am Main is the third largest university in Germany with about 46,000 students and 4,600 employees. It is an internationally recognised university and an important regional employer. In recent years, the Goethe University was completely restructured to now centre on two campus locations for natural sciences and humanities/social sciences, which offer an ideal research and study environment. In 2008, the ‘Goethe University became a foundation under public law – a unique status among German universities, which allows great autonomy.


The temporary employment for research assistants follows the rules of the Wissenschaftszeitvertragsgesetz in conjunction with the university law of Hesse (Hessisches Hochschulgesetz).


The BMLS is an equal opportunities employer and strongly encourages applications of female scientists. Persons with disabilities and equivalent qualification will be given priority.


Apply with CV and Cover Letter

Must be a .doc, .docx, or .pdf file and no larger than 1MBMust be a .doc, .docx, or .pdf file and no larger than 1MB

PhD Position in RNA Bioinformatics