University of Southern Denmark (SDU)

PhD Position in Long Noncoding RNA and Metabolic Diseases in an ERC and DDA Funded Research Group

University of Southern Denmark (SDU)

Odense M, Denmark

The position:
A PhD scholarship (financed by the Danish Diabetes Academy DDA) for three years is available at the Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense. Employment is possible from 1 May 2020 or soon thereafter.

We offer:
* A three-year fully financed PhD position in a stimulating and supportive, international research environment.
* Possibility for faculty membership in the Danish Diabetes Academy.
* Access to state-of-the art equipment, facilities and infrastructure (see below).
* A competitive salary and social benefits (eg. health coverage, parental leave, social security etc.).
* Dedicated assistance and support with various practical, social, and legal aspects (housing, visa, administration, tax etc.), especially for international candidates through out International Staff Department and department.
* Interaction with researchers from the Center for Adipocyte Signaling (ADIPOSIGN) and Center for Functional Genomics and Tissue Plasticity (ATLAS).

Your profile:
We are seeking an ambitious employee with a life science background who is interested in carrying out research projects on the epigenomic control of liver and hepatocyte physiology in an international team of scientists. The ideal candidate will be:
* Performing characterization of recently identified obesity- and T2D associated long noncoding RNAs (Pradas-Juni 2020 Nat Commun) using CRISPR/Cas9-mediated gene activation / inactivation approaches in vitro / vivo.
* Analysing and obtaining novel datasets from Next-Generation Sequencing experiments (RNA-Seq, ChiP-Seq).
* Handling and phenotyping knockout mice for obesity- and T2D-associated long noncoding RNAs and primary hepatocyte cell culture.
* Contributing to teaching activities in English in the group and for the department.

The ideal candidate should fulfil as many of the following requirements as possible:
* An MSc degree in life sciences (biologist, biochemist or related degree).
* Practical background in noncoding RNA biology, metabolism and / or chromatin regulation.
* Willingness to work with transgenic mice and certification in Laboratory Animal Science (EU function ABD or former FELASA B).
* Solid background in bioimaging (ISH, single-molecule FISH).
* Experience and / or genuine interest in learning scripting languages (R, Python) to analyse – OMICS datasets.
* Good collaborative skills, a positive attitude towards science and its contribution to society.
* Diligence and intellectual flexibility.
* An open and positive mind that actively contributes to the infrastructure and the success of the research team and the department.

Deadline: 10 April 2020.

Please see the full call, including how to apply, on

Please apply via recruiter’s website.