Certara USA, Inc.

PBPK Consultant and Scientific Advisor

Certara UK

Sheffield, London, Cantebury, Daresbury, United Kingdom

PBPK Consultant and Scientific Advisor – Certara UK, Simcyp Division

Closing Date for Applications: Tuesday, 21st January 2020
Line of Management: Head of PBPK Consultancy
Position Type: Full Time
Holiday Entitlement: 25 days, plus statutory bank holidays
Salary: £40,000-£70,000 per annum dependent on qualifications and experience (plus discretionary bonus, pension contribution, health scheme etc.)
Location: Flexible

Job Overview:
We have an immediate opening for a highly motivated and talented PBPK Consultant and Scientific Advisor with a DMPK and PBPK modelling background. The candidate should have a knowledge of the application of PBPK modelling in drug discovery and/or development and its acceptance across various regulatory bodies. The role involves leading consultancy projects with clients in the Pharmaceutical Industry to develop PBPK models for particular projects of interest. More specifically the candidate will apply PBPK models in support of a number of applications including but not limited to the following: DDI liability prediction; food effect prediction; PK prediction in special populations and biopharmaceutics/bioequivalence prediction.

The successful candidate will join an internationally recognised, multidisciplinary company, providing opportunities for further development of knowledge and skills. We offer a unique and exciting mix of academic and commercial environments that encourage regular attendance at scientific meetings as part of our continuous education programmes. As such, they will be expected to keep abreast of the latest scientific developments in the area of PBPK and IVIVE. In addition, they will have good communication skills and will actively engage with peers and clients within industry, academia and regulatory agencies.
The post is computer based and does not include routine laboratory or clinical work.

Requirements:
Essential
 PhD degree or equivalent in a relevant field with at least 4 years of experience in the field of DMPK/PBPK/IVIVE
 Familiarity with mechanistic biological models and/or PBPK models of small and/or large molecules
 Some level of visibility in the scientific community in terms of publications/presentations in scientific journals and at conferences
 Working knowledge of common or specialised modelling and simulation platforms, such as Simcyp, Phoenix, etc
 Good communication skills, as evident by presentation at scientific meetings, and good interpersonal and organizational skills

Desirable
 Hands-on knowledge of PBPK modelling software e.g. Simcyp
 Awareness of R&D process in pharmaceutical companies

Company Overview:
Simcyp is part of Certara, a company which combines sophisticated research and development informatics with the power of predictive science methodologies to span the drug development spectrum and offer pharma a previously unavailable ‘end-to-end’ solution in the quest for improving human health. The Simcyp team conducts cutting-edge research and provides consultancy, knowledge integration tools, algorithms, modelling solutions and databases (implemented in its globally-recognised Simcyp Population-based Simulator) for a client base of major blue-chip pharmaceutical and biotechnology organisations. Simcyp focuses, in particular, on gathering information required for the modelling and simulation (M&S) of the individual time-course and fate of drugs. We are on course to become the global industry standard, consequently, there is a continuous requirement for high quality people to join us, help in our expansion and share in our success.

Applications: Please apply via workforcenow.adp.com

Please apply via recruiter’s website.

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