Applications are invited from suitably qualified candidates for one full-time fixed term position as Early Stage Researcher /PhD student with CÚRAM, SFI Research Centre for Medical Devices at the National University of Ireland, Galway.
The position, funded by the Horizon 2020 programme of the European Union, is available from January 2020. The appointments will be on a temporary basis for a maximum period of three years (regular full-time employment contract).
Musculoskeletal diseases are reported to affect roughly half of those over 60, strongly impacting the quality of life. They are a major burden on individuals, healthcare and welfare systems, with huge direct and indirect costs. Treatment of musculoskeletal disorders is often based either on prosthetic rehabilitation or on regenerative surgical procedures, including scaffold implantation. In both cases, individual tissue healing and regeneration response, and the appropriateness of the implanted device, markedly affect the outcome. Improvement can be achieved by precision medicine, specifically designed on patients’ individual characteristics. The ultimate goal of PREMUROSA project, is to train a new generation of scientists with an integrated vision of the whole value chain in musculo-skeletal regeneration technologies and able to boost the necessary innovations to achieve precision principles in developing innovative devices and optimized clinical applications. This aim will be achieved by a “triple i” (interdisciplinary, intersectoral, international) approach of thirteen ESRs, who will benefit from an excellent scientific environment, up-date technologies and supervision by international leaders in the field. The candidate will learn to integrate academic and industrial aspects and will sharpen their experimental and complementary skills in a well-designed and diversified and unprecedented training program.
The Centre for Research in Medical Devices (CÚRAM – www.curamdevices.ie) is a national, SFI funded, €49.6m research centre that brings together researchers from across Ireland. The prime objective for CÚRAM is to radically improve health outcomes for patients by developing innovative implantable ‘smart’ medical devices to treat major unmet medical needs. Implants will be designed and manufactured to respond to the body’s environment and to deliver therapeutic agents, such as drugs, exactly where needed. Cutting-edge science will develop devices using the very latest research from biomaterials, stem cells and drug delivery and the support of strong clinical collaborations, industry partners and hospital groups to enable rapid translation to the clinic.
We seek a candidate to join our interdisciplinary research team working in the field of Biomaterials and Regenerative Medicine. The focus of our research is to design and validate a customized hydrogel for repair and regeneration of the nucleus pulposus (NP) of intervertebral discs (IVD). We are interested in understanding the interactions between ECM with biomaterials and cells and then using this knowledge to design and develop novel customized biomaterials that mimicking the native composition of the IVD nucleus pulposus.
Duties and Responsibilities:
Develop and validate a novel customized optimized hydrogel (mimicking the native composition of the IVD nucleus pulposus) functionalized with specific glycans and patient-derived bone-marrow-derived stem cells to replicate the NP cell ECM microenvironment.
Participate in training events for researchers and Principal Investigators involved in the programme
Liaise and report to the Project Manager, which includes contributing to periodic scientific reports
Contribute to the reporting of project milestones and deliverables in accordance with EU deadlines
Promote and disseminate results from the programme, which includes contributing to newsletters and participating in outreach events
The candidate should have a 1st class or a 2:1 honours first degree and a Master’s in any of the following areas: Biomaterials, Biomedical Engineering, Chemistry, Molecular Biology, Biotechnology, Tissue Engineering, Medicine, Cell Biology, Biology, Drug Discovery or in a related area.
Less than four years’ full time-equivalent research experience and has not yet been awarded a doctoral degree (PhD)
Resided less than 12 months in Ireland in the last three years
Excellent communication and organisation skills
Fluent in spoken and written English
Excellent writing and presentation skills
Flexibility and ability to work in a team environment
Availability to travel nationally and internationally two to three times a year
The ideal candidate should have experience in as many of the following techniques: Cell (fully differentiated and Stem cells) Biology; Molecular Biology; Protein / Gene analysis; Histology; and Immunohistochemistry, Biomaterial fabrication/synthesis.
Candidates should have excellent communication and organisational skills; be highly motivated and passionate about developing new products; and have strong written, oral and interpersonal skills. The candidate should be able to work independently and as a part of team. Leadership skills are desirable for this fellowship.
The candidate will be working under the supervision of Prof. Abhay Pandit http://www.curamdevices.ie/curam/about-us/our-people/director/professor-abhay-pandit.html
Salary: The remuneration will be in line with the European Commission rules for Marie Skłodowska-Curie grant holders (Early-Stage Researchers, Initial Training Network).
Start date: Position is available from January 2020
Continuing Professional Development/Training:
Researchers at NUI Galway are encouraged to avail of a range of training and development opportunities designed to support their personal career development plans.Further information on research and working at NUI Galway is available on Research at NUI Galway.
For information on moving to Ireland, please see www.euraxess.ie.
Applications (in English) should include a CV (Please use the Europass template: https://europass.cedefop .europa.eu/editors/en/cv/compose), certificates of examination grades, a motivation letter (max. one page) describing your research career goals, skills and experience, as well as two letters of recommendation.
Please send applications by e-mail (in PDF only) to firstname.lastname@example.org. Please quote the project name and reference number “NUIG-213-19” in the subject line of e-mail application. For research related enquires please contact Raghvendra Bohara at ”mailto:Raghvendra.Bohara@NUIGalway.ie">Raghvendra.Bohara@NUIGalway.ie.
Closing date for receipt of applications is 5.00 pm on 22nd November 2019
All positions are recruited in line with Open, Transparent, Merit (OTM) and Competency based recruitment.
National University of Ireland, Galway is an equal opportunities employer.