The Laboratory of Pathology (LP) of the National Cancer Institute (NCI) at the National Institutes of Health (Bethesda, MD) is seeking an NGS Data Scientist with expertise in Next Generation Sequencing (NGS) to participate in our expanding clinical genomic program. In particular, the LP-NCI has several NGS-based assays to identify genetic changes in clinical samples derived from cancer patients seen by the Intramural program of the National Cancer Institute. The Scientist will work with pathologists, bioinformaticians, wet lab scientists and support staff in the Laboratory of Pathology to analyze data and generate clinical pathology reports.
The essential responsibilities will include: identify, annotate and investigate the clinical significance of variants found in NGS-based clinical tests; prepare variant assessment summary, classify variants as per AMP/CAP guideline; and, assist with literature review and interpretation of variant data. In addition, the Scientist will participate in quality assurance activities, training , and regulatory management of these clinical genomics activities in the Laboratory of Pathology. The Scientist will also interact with oncologists and pathologists and/or pathologists-in-training throughout the National Cancer Institute at forums such as molecular tumor boards related to these genomic analyses of clinical samples, and to participate in the preparation of manuscripts resulting from these projects. Finally, the Scientist will continue to innovate as this sequencing program progresses and will explore new methods and technologies for genome-wide assessment of tumor samples.
The requirements for this position are a PhD or Master’s level (or equivalent degree) in molecular biology, human genetics or a related field. This position also requires substantial experience in the NGS field, either as part of a postdoctoral research training program or through direct participation in an NGS testing facility. Beyond an extensive background in NGS technology, the position requires experience with the application of bioinformatic and statistical tools and the analysis of genomic databases. Finally, strong written and oral communication skills as well as managerial and organizational experience are also required.
This Scientist position is being recruited as a long-term contract position. Salary will be commensurate with research experience in the NIH system.
The Laboratory of Pathology within the intramural program of the CCR, NCI, NIH, is located in Bethesda, Maryland, USA. Its mission is to achieve the highest level of quality in clinical diagnostics, cancer research and education. Training programs are made available through the NCI Training Office and the NIH Office of Intramural Training and Education. The NIH is dedicated to building a diverse community in its training and employment programs.
This position is at the National Cancer Institute, and is therefore subject to a background investigation. The NIH is dedicated to building a diverse community in its training and employment programs.
How To Apply:
Suitably qualified candidates should submit their curriculum vitae, cover letter, and the names and contact information (email and phone #) for three references to:
Dr. Joseph Chinquee
Laboratory of Pathology
Center for Cancer Research
National Cancer Institute, NIH
Bethesda, MD 20892-1500