MRC London Institute of Medical Sciences (LMS)

MRC Postdoctoral Research Scientist

MRC London Institute of Medical Sciences

London, United Kingdom

MRC Postdoctoral Research Scientist
Single Molecule Imaging Group
Fixed Term, 3 years
£33,712 – £37,425 pa inclusive of allowances
London, UK

The Single Molecule Imaging Group, led by Professor David Rueda, at the MRC London Institute of Medical Sciences (LMS), and the Department of Medicine at Imperial College London, is offering a 3-year Postdoctoral Position in Biophysics.

Job Description
We have recently developed a fluorgenic RNA (Mango) aptamer-based approach to image individual RNA molecules in live cells (Autour et al 2018 Nature Communications and Cawte et al 2019 in revision). We now seek a postdoctoral researcher to further exploit this technique to image various RNA processing mechanisms, such as gene expression, RNA splicing, RNA localization and RNA decay in live mammalian cells. Using this approach, we aim to elucidate the mechanisms regulating these RNA processing steps.

You must have a PhD (or equivalent experience), with a strong background in biophysics, quantitative biology or related disciplines. Candidates should be familiar with several of the following techniques: light microscopy, mammalian tissue culture, RNA transcription and processing, programming (e.g., python, Matlab, Labview, etc), image analysis (e.g. ImageJ) and quantitative data analysis. Equally important are outstanding creativity and enthusiasm for interdisciplinary science. Excellent English communication skills (spoken and in writing) are required.

The London Institute of Medical Sciences (LMS) is an institute funded by the Medical Research Council (MRC) and is a division of the Faculty of Medicine at Imperial College London. Based on the Hammersmith Hospital Campus in West London (W12), the LMS has first class facilities and provides investigators from clinical and basic science backgrounds with the opportunity to pursue innovative, multidisciplinary research within the established clinical base of Imperial College. For more information, visit

This is an MRC Postdoctoral Scientist position providing training and development supporting post-doctoral scientists in early or changed career paths helping establish them as successful research scientists in their chosen field.

The MRC London Institute of Medical Sciences is a research institute within UK Research and
Innovation. UK Research and Innovation is a new entity that brings together nine partners to create an independent organisation with a strong voice for research and innovation, more information can be found at

For full details of this post (Job Description and Person Specification) and to complete an online application, visit:
Please quote reference number LMS 1139.

Applications should include
o a cover letter indicating the motivation to apply for this position,
o a CV including a publication list,
o a concise description of previous research accomplishments (<1 page), and
o contact details of at least 2 approachable academic referees

Closing date: 1st September 2019

Final appointment will be subject to pre-employment screening

*Salary quoted is inclusive of London weighting. Additional allowances comprise a £1,000 lump sum Settlement Allowance plus a yearly Training Allowance of £850 in the first year, paid in monthly installments. The Training Allowance increases to £1,300 in year two, and £1,800 in the third year.

Please apply via recruiter’s website.