IMT 20-20 Bachelor or Master Thesis: Characterization of motility in microorganisms on substrates using MEMS tools

Karlsruhe Institute of Technology (KIT)

Karlsruhe, Germany

Area of research:

Diploma & Master Thesis


Part-Time Suitability:

The position is suitable for part-time employment.


Starting date:

17.08.2020


Job description:

Cyanobacteria is one of the most important and oldest class of bacteria on earth. Additionally, they have very interesting characteristics and exhibit intriguing behavior. More specifically, Cyanobacteria can produce their own food through photosynthesis and move in response to light – behavior which is called phototaxis.

The study of phototaxis of cyanobacteria is the topic of the present project. You will be using the tool-set specific to lab on a chip (LOC) and microfluidic devices in order to investigate phototaxis of cyanobacteria within microfluidic chips. Furthermore, you will be trained in MEMS-based characterization techniques in order to subsequently characterize the bacterial cells, their movement on various substrates and in the end, record the overall response of cell motility as a function of different surface properties.

The specific tasks within the project will be: (i) training on MEMS characterization techniques such as contact angle measurements, atomic force microscopy (AFM), Zeta potential measurement and white light Interferometry ; (ii) cell culture, cell handling and testing on a Microscopic setup; (iii) statistical analysis of the data;

You will be integrated in a larger team within the SPA-Lab. Within this project, you will use the infrastructure existent at the Institute of Microstructure Technology (IMT), i.e., microfabrication facilities and micro-characterization equipment. This is a complete project, offering the possibility to fabricate and test the devices, giving you the opportunity to co-author conference and/or journal publications

Further information on the Institute of Microstructure Technology (IMT): www.imt.kit.edu

This research center is part of the Helmholtz Association of German Research Centers. With more than 42,000 employees and an annual budget of over € 5 billion, the Helmholtz Association is Germany’s largest scientific organisation.

Please apply via recruiter’s website.

Quote Reference: 15148453