Astex Pharmaceuticals Limited

High Throughput Experimentation Chemist (Ref: EC/0619)

Astex Pharmaceuticals

Cambridge, East of England, United Kingdom

High Throughput Experimentation Chemist (Ref: EC/0619)

Full time

Cambridge, UK

Astex Pharmaceuticals is a world leader in innovative drug discovery and development. The company has successfully applied its proprietary Fragment-Based Drug Discovery platform to generate multiple new drug candidates that are progressing in clinical development. Successful collaborations have led to two launched oncology drugs (Kisqali® partnered with Novartis and BalversaTM partnered with Janssen). Astex continues togrow and focuses on Oncology and Neurological Disorders.


We currently have an opportunity within our Medicinal Chemistry department in Cambridge, UK for an outstanding synthetic organic chemist with hands-on experience of laboratory automation and a proven record of high-quality scientific achievement.

Role Overview

The successful candidate will lead the development of Astex’s high throughput experimentation platform for synthetic organic chemistry and its application to fragment-based drug design and drive the development of novel methodology for fragment synthesis and fragment hit elaboration. They will also provide training for the chemistry department in the use of robotics and facilitate collaborations with academia on cutting-edge synthesis technology.

Candidates will have a PhD in the field of synthetic organic chemistry and at least two years’ post-doctoral experience in a leading academic institution. A broad knowledge of organic synthesis is essential, including familiarity with latest developments in the fields of photoredox, CH activation, electrochemistry, late stage functionalisation and other emerging areas. The candidate will have a good network of academic contacts, excellent communication skills and ability to work effectively as part of a multi-disciplinary team.

We offer excellent training and career development opportunities as well as a highly competitive salary and benefits package.

To apply, please send your CV and a cover letter quoting the job reference: EC/0619 to

For information on Astex Pharmaceuticals please visit: and for information on Otsuka Pharmaceuticals please visit:


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High Throughput Experimentation Chemist (Ref: EC/0619)