German Cancer Research Center in the Helmholtz Association (DKFZ)

Group Leader in Bioinformatics

German Cancer Research Center in the Helmholtz Association (DKFZ)

Heidelberg, Germany

The German Cancer Re­search Center is the largest bio­medi­cal re­search insti­tu­tion in Germany. With more than 3,000 employees, we operate an exten­sive scien­tific program in the field of cancer research.

The Division of KiTZ Heidelberg and the Division of Pediatric Neurooncology at DKFZ is seeking a

Group Leader in Bioinformatics
(Ref-No. 2022-0212)

We are looking for a group leader in bioinformatics to head a multi-disciplinary research group of 8-10 members at KiTZ ( and the Division of Pediatric Neurooncology at DKFZ (

Job description:
- Lead and execute integrative research projects aimed at identification and validation of disease mechanisms and therapeutic opportunities, which will enable the develop­ment of mechanism-of-action-based therapies for pediatric cancer
- Oversee the development of computational approaches and efficient workflows to gain insights from large, complex and multi-dimensional datasets (bulk and single-cell multi-omics and integration of clinical data) with the aim of utilizing these for diagnostic applications
- Lead the bioinformatics team of the KiTZ international pediatric precision oncology program (

What to expect in the position as goup leader:

- A welcoming and supportive international group of highly collaborative colleagues that will help you achieve your scientific and career goals
- Access to large clinical and cancer omics datasets and sample collections as well as an outstanding environment for paediatric oncology research
- Access to a state-of-the-art computing cluster for data processing and downstream analysis
- Access to the Omics IT and Data Management Core Facility (ODCF), that provides high-throughput computing, data management and basic bioinformatics services
- Strong focus on pediatric cancer biology, translational research and precision medicine
- Interdisciplinary projects connecting biology with medicine and discovery with translation
- Close interactions with physicians and clinical researchers

- Candidates need to have a PhD in bioinformatics, computational biology, computer science or a related area as well as significant postdoctoral research experience and a strong publication record
- Expertise in genomics and bioinformatics, specifically in the computational analysis and interpretation of high-dimensional next-generation sequencing (NGS) data from cancer genomes
- Deep understanding of data analysis for high-throughput biological assays, including single-cell approaches
- Expertise in high-performance computing plus contemporary bioinformatics and computational research approaches, methods and software
- Proficiency in relevant programming / scripting languages (e.g. Python, R)
- Able to manage and coordinate research projects at the interface of genomics, precision oncology and bioinformatics
- Able and interested in leading and managing a translational research group
- Independent and self-reliant way of working, characterised by a high degree of initiative and sense of responsibility
- Able to collaborate externally and internally and work within a team to achieve shared goals
- Both support and independently initiate the acquisition of third-party funding
- Verbal and written English language fluency

We offer:
- Interesting, versatile workplace
- International, attractive working environment
- Campus with modern state-of-the-art infrastructure
- Salary according to TV-L including social benefits
- Possibility to work part-time
- Flexible working hours
- Comprehensive further training program

The position is initially limited to 2 years with the possibility of prolongation.
The position can in principle be part-time.

Important notice:
The DKFZ is subject to the regulations of the Infection Protection Act (IfSG). As a consequence, only persons who present proof of immunity against measles as well as against COVID-19 may work at the DKFZ.

For further information please contact
Prof. Dr. Stefan Pfister, phone +49 (0)6221/42-4618.

The DKFZ is committed to increase the proportion of women in all areas and positions in which women are underrepresented. Qualified female applicants are therefore particularly encouraged to apply.

Among candidates of equal aptitude and qualifications, a person with disabilities will be given preference.

To apply for a position please use our online application portal (

We ask for your understanding that we cannot return application documents that are sent to us by post (Deutsches Krebs­forschungs­zentrum, Personal­abteilung, Im Neuen­heimer Feld 280, 69120 Heidelberg) and that we do not accept applications submitted via email. We apolo­gize for any inconvenience this may cause.

Please apply via recruiter’s website.