PhD Student Position in Virology, Immunology and Cell Signaling
at the Institute of Cell Biochemistry, Hannover Medical School (MHH), for more details about the Institute see https://www.mhh.de/zellbiochemie.
The successful candidate will study the function of the adenoviral protein E3/49K in immunomodulation (Windheim et al. (2016) J. Biol. Chem. 291, 6796-6812; Windheim et al. (2013) Proc. Natl. Acad. Sci. 110, E4884-4893; Windheim & Burgert (2002) J. Virol. 76, 755-766). The E3/49K protein targets the tyrosine phosphatase CD45 and counteracts the antiviral activities of immune cells to enable adenovirus replication and propagation. However, the molecular details of this mechanism are still elusive and will be addressed in this project. We offer a salary of 65% TV-L E13 for three years (extension possible).
We seek highly motivated applicants who would like to benefit from an attractive scientific environment studying a fascinating novel mechanism to regulate immune cell signal transduction. If you combine curiosity, enthusiasm, imagination and a “can do”-mentality with a strong interest in the molecular mechanisms of signaling events, please forward your full application including a motivation letter, a detailed curriculum vitae, copies of degree certificates and transcripts as well as the contact details of two referees in English or German via email to Dr. Mark Windheim (Windheim.Mark@mh-hannover.de).
Requirements: Applicants should have obtained or be close to obtain degrees eligible for PhD studies. Experience with standard techniques of biochemistry, cell culture and molecular biology and excellent communication skills in English are expected.
The Hannover Medical School is one of Germany’s leading medical universities providing excellence in biomedical research, medical education and health care. The Institute of Cell Biochemistry addresses important questions in one of the four major integrated areas of research conducted at the MHH: “Infection, immunity and inflammation research”.