Brigham and Women's Hospital (BWH)

Genetics and epigenetics of chronic pain and migraine

William Renthal, M.D., Ph.D.

Boston, MA, United States

The Renthal lab is located in the new Hale Building for Transformative Medicine at the Brigham and Women’s Hospital/Harvard Medical School. The lab focuses on pain and headache genetics. Current projects in the laboratory involve generating single-cell gene expression datasets from mouse and human sensory ganglia. We are particularly interested in the function of genes that are selectively expressed in nociceptors, which will be explored in vitro and with animal models of pain. The lab also focuses on transcriptional and epigenetic mechanisms underlying cell-type-specific gene expression in nociceptors with the goal of leveraging this biology toward the development of more selective pain therapeutics. These studies will require skills in molecular biology, single-cell genomics, bioinformatics, calcium imaging, and mouse tissue and behavioral assays. Preference will be given to candidates who are familiar with using R and/or python to work with large datasets. The department will appoint you to the BWH Medical Staff as a Research Fellow and will propose that you be appointed as a Research Fellow at the Harvard Medical School (HMS); however, final approval of this appointment rests with HMS


Learn more at http://renthal.bwh.harvard.edu


To apply, please email your CV, cover letter detailing research your experience and interests, and the contact information of three references.   

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Position

Genetics and epigenetics of chronic pain and migraine