Fully Funded Postdoctoral Research Position in Microbial Genomics, Antibiotic Resistance and Evolution
Organization: U.S. Department of Defense (DoD)
Site: Walter Reed Army Institute of Research (WRAIR), Silver Spring, MD
Fellowship: The Oak Ridge Institute for Science and Education (ORISE)
About us and our mission:
The Walter Reed Army Institute of Research (https://www.wrair.army.mil/) is a World-Class organization that conducts biomedical research that aims to deliver life saving medical knowledge, technology and material to sustain Warfighter readiness. Within WRAIR, the Multidrug-Resistant Organism Repository and Surveillance Network (MRSN) is a unique entity that serves as the primary surveillance organization for antibiotic-resistant bacteria across the Military Healthcare System (MHS). The laboratory receives and processes (routine ID, AST and WGS) 500-800 new isolates of ESKAPE+ pathogens every month from military hospitals across the world, and routinely collaborates with other U.S. Government agencies, allied nations, and academic research institutions. Our work directly impacts the DoD and MHS by:
- Providing real-time genomic analysis of the evolution, prevalence and mobility of “superbugs”
- Conducting retrospective and prospective bacterial outbreak analyses across the entire enterprise.
- Assisting healthcare centers and infection control services to detect and respond to outbreaks
About the position:
The fellow will spearhead the comparative genomic analysis of hundreds of epidemiology-linked isolates (ongoing outbreaks in military hospitals) of MDR Enterococcus spp. Staphylococcus spp., Klebsiella spp., Acinetobacter spp., Pseudomonas spp., Enterobacter spp., and Escherichia coli with the goal of identifying the factors that influence the emergence of MDR populations, their distinguishing characteristics, and the evolutionary drivers that shape them. In this mission, the fellow will receive mentorship from experts in the field of bacterial genomics and antimicrobial resistance and will be assisted by a team of 2-3 junior computational scientists. Initial appointment is for 12 months with the possibility for renewal. Transition to a more permanent position is also available, contingent on performance.
Candidates should have experience with Illumina sequence generation and analysis and a PhD in bacterial genomics/computational biology with broad experience of comparative genomics and evolutionary analyses. Some knowledge on the epidemiology of ESKAPE+ pathogens and their clinically relevant antimicrobial resistances is desirable. Candidates should be capable of writing scripts in languages such as Python and common software packages such as R.
Criteria for eligibility:
- U.S. Citizen or permanent resident only.
- Doctoral Degree in computational biology, biological sciences (bacteriology, epidemiology, evolutionary biology, infectious diseases, microbiology) or related fields received within the last 60 months.
- Stipend ($75-$90K) commensurate with academic standing and experience.
How to apply:
- Applications should be received by the closing date of June 28, 2019
- All applicants must apply online at: https://www.zintellect.com/Opportunity/Details/MRMC-WRAIR-2019-0002
- Informal enquiries encouraged at usarmy.detrick.medcom-wrair.mbx.WRAIR-MRSN@mail.mil