Wellcome Trust Sanger Institute

Faculty Position with Open Targets

Wellcome Sanger Institute

Cambridge, United Kingdom

Open Targets at The Wellcome Genome Campus is seeking an exceptional mid-career stage scientist to join its Core Faculty to lead a research team for Open Targets and contribute to the Institute’s scientific portfolio. Positions carry a significant core package of salary and benefits as well as support backed by rewarding and flexible employment terms including many family friendly initiatives. Our exceptional core funding enables faculty to focus their energy on science.

The Opportunity
You will develop a world-class research programme and lead a team that will advance the field of target identification and validation. We welcome candidates in any combination of the following or other areas that might be relevant to the research interests of the Sanger and Open Targets:
• Applications of genetics approaches to drug discovery including experimental approaches that improve target identification from GWAS data.
• Development and use of cellular models in one of the Open Targets Therapeutic Areas, Oncology, Immunology & inflammation, Neurodegeneration.
• Exploiting single cell genomics approaches in disease relevant models.
• Aspects of drug development including validation of targets in a specific disease area.
• Machine learning approaches to improve target selection.

More about Open Targets
Open Targets is a pioneering public-private partnership between EMBL-EBI (European Bioinformatics Institute), GlaxoSmithKline (GSK), the Wellcome Sanger Institute (Sanger), Celgene, Sanofi and Takeda, located on the Wellcome Genome Campus in Hinxton, near Cambridge, UK.

Open Targets brings together expertise from six complementary institutions to generate evidence on the biological validity of therapeutic targets and provide an initial assessment of the likely effectiveness of pharmacological intervention on these targets, using genome-scale experiments and analysis. Open Targets aims to provide an R&D framework that applies to all aspects of human disease, to improve the success rate for discovering new medicines and share its data openly in the interests of accelerating drug discovery.

Essential Skills
• Demonstrated record of scientific accomplishment
• Effective communicator with and ability to develop and maintain relationships inside and outside area of expertise
• Experience of presenting scientific data to diverse audiences
• Inspirational, conveys a passion and direction which motivates team; instils pride and feeling of success
• Has a clear vision and is able to communicate this vision.
• Demonstrates inclusivity and respect for all
• Can engage stakeholders, learners and decision-makers
• Is flexible and adaptable to changing circumstances
• Previous management or supervision of technical/professional individuals and groups
• Experience of managing projects

Other information
Our campus

Set across 130 acres, just outside of Cambridge, The Sanger Institute is located on the stunning Wellcome Genome Campus. Home to some of the world’s foremost institutes and organisations in genomics and computational biology, committed to delivering life-changing science with the reach, scale, and creativity to solve some of humanity’s greatest challenges.

Our Open Approach
We appreciate the importance of achieving work-life balance and support this with a number of family and carer-friendly policies. Plus a flexible working policy for those who may wish to amend their working pattern or arrangement.

Being part of the Genome Wellcome Campus you will be part of the beautiful working environment with an impressive range of benefits, services and facilities also including:
• Free bus service to and from Campus, covering various routes around Cambridge, Saffron Walden and surrounding villages
• A car-share initiative
• Free parking
• A number of on-site venues where you can meet, eat and socialise with colleagues
• A thriving Sports and Social Club which provides members with subsidised access to a gym, tennis courts, sports hall, fitness classes and a vibrant social calendar of events

We hold an Athena SWAN Bronze Award and will consider all individuals without discrimination and are committed to creating an inclusive environment for all employees, where everyone can thrive.

To find out more about the role and the benefits we offer, please click on the Recruitment Pack at the bottom of the page

Find out more
For further information on the Sanger Institute and Open Targets. https://www.sanger.ac.uk/
For a discussion about the role, contact Ian Dunham in the first instance id1@sanger.ac.uk

Application checklist
Applications should be accompanied by:
• Curriculum vitae, complete list of publications and details of three referees;
• A two page description summarising scientific achievements to date; and
• A three page outline of future research plans indicating how these fit with the Open Targets remit of target identification and validation and contribute to and make use of Sanger programmes and infrastructure.

Closing date for applications: 31st October 2019
Interviews will be held: Mid-November

Please apply via recruiter’s website.