CRUK Beatson Institute for Cancer Research

Experienced Cell Biologist

CRUK Beatson Institute for Cancer Research

Glasgow, Scotland, United Kingdom

Experienced Cell Biologist

Starting salary £30,000 – £41,000 (Depending on experience) – 3 year contract

The Drug Discovery Unit at the Beatson Institute in Glasgow, is one of four Cancer Research UK funded Drug Discovery Units across the UK. The aim of these units is to work closely with local cancer experts to maximise the opportunity to develop new and innovative therapies that strike at the core of cancer pathology. Using state of the art screening and structural biology technology, industry standard medicinal chemistry and complex biological modelling systems, the Drug Discovery group at the Beatson is tackling some of the most challenging targets in cancer biology today. One such target that has eluded drug discovery efforts over the years is KRAS. Highly mutated in cancer, KRAS has proved difficult to target. Harnessing the significant capability of the Beatson Drug Discovery Unit we have developed a highly competitive KRAS inhibitor project.

An exciting opportunity has arisen within the Beatson Drug Discovery Unit to join a three year collaboration project with Novartis to develop RAS inhibitor compounds for the treatment of KRAS driven cancers for which there is a substantial unmet clinical need.

We are looking for an experienced cell biologist with knowledge of the RAS/MAPK field to contribute to the development of cellular assay systems.

You will be expected to work to a high standard and generate data within specific timelines to achieve project objectives. You will have excellent written and oral communication skills, a creative approach to problem solving and the ability to interpret and present complex data sets. You will also have good interpersonal skills, a strong work ethic and enjoy working within a multi-disciplinary team of scientists.

Skills and Experience:
 PhD or equivalent experience in a relevant biological discipline
 Knowledge of the RAS/MAPK field
 Industrial experience within a drug discovery environment would be an advantage
 Experience in mammalian cell culture systems and cellular assays such as proliferation and viability is expected and experience with 3D cell culture and CRISPR/siRNA would also be an advantage
 Strong knowledge of cancer biology, cell pathology and signalling pathways

Informal enquiries are welcome and should be addressed to Dr Francesca Pellicano;

All applications must be made via our website at

Closing date for applications is Friday 20th March 2020

Please apply via recruiter’s website.