German Cancer Research Center in the Helmholtz Association (DKFZ)

Computational Postdoc Position in Linking the Microbiome to Therapy Response

German Cancer Research Center in the Helmholtz Association (DKFZ)

Heidelberg, Germany

The German Cancer Re­search Center is the largest bio­medi­cal re­search insti­tu­tion in Germany. With more than 3,000 employees, we operate an exten­sive scien­tific program in the field of cancer research.

The German Cancer Research Center (DKFZ) is offering a

Computational Postdoc Position in Linking the Microbiome to Therapy Response
(Ref-No. 2022-0238)

We offer a position for a bioinformatician interpreting next-generation sequencing data within a clinical trial at the National Center for Tumor Diseases (NCT) Heidelberg and the German Cancer Research Center (DKFZ). You will work in a team of bioinformaticians embedded in a division of molecular biologists and collaborate with clinicians to identify the link between the bacterial and viral microbiome and targeted treatments for breast cancer patients. The position will be situated in the Division of Molecular Genetics at DKFZ.

DKFZ is situated in a large campus in Heidelberg, Germany. The campus is also housing the University Hospital as well as many university departments and research institutes.

The bioinformatician will work together with experienced bioinformaticians and clinicians to analyze whole genome and transcriptome sequencing data of breast cancer patients and reference cohorts identifying microbiome components. The analysis results aim to understand the microbiome components in breast cancer and finally lead to improved personalized treatment recommendations. The findings will be validated by wet lab scientist on clinical samples originating from the clinical trial. Furthermore, the applicant is expected to improve already-established analysis pipelines to identify microbiome components based on next-generation sequencing data of genome and transcriptome. In addition, the applicant will have the opportunity to develop their own research projects in collaboration with the experimental groups within the division.

Your profile:
Bioinformatician must hold a master’s degree (M.Sc.) and Phd with several years of professional experience in the analysis of next-generation sequencing data, ideally in the interpretation of microbiome components. Knowledge of breast cancer biology and the human immune system is an advantage. Working language is English.

We offer:
- Interesting, versatile workplace
- International, attractive working environment
- Campus with modern state-of-the-art infrastructure
- Salary according to TV-L including social benefits
- Possibility to work part-time
- Flexible working hours
- Comprehensive further training program
- Access to the DKFZ International Postdoc Program

The position is limited to 2 years.
The position can in principle be part-time.

Important notice:
The DKFZ is subject to the regulations of the Infection Protection Act (IfSG). As a consequence, only persons who present proof of immunity against measles as well as against COVID-19 may work at the DKFZ.

For further information please contact
Dr. Marc Zapatka, phone +49 (0)6221/42-4584.

The DKFZ is committed to increase the proportion of women in all areas and positions in which women are underrepresented. Qualified female applicants are therefore particularly encouraged to apply.

Among candidates of equal aptitude and qualifications, a person with disabilities will be given preference.

To apply for a position please use our online application portal (

We ask for your understanding that we cannot return application documents that are sent to us by post (Deutsches Krebs­forschungs­zentrum, Personal­abteilung, Im Neuen­heimer Feld 280, 69120 Heidelberg) and that we do not accept applications submitted via email. We apolo­gize for any inconvenience this may cause.

Please apply via recruiter’s website.