General Information: The Sahay Lab at the Department of Pharmaceutical Sciences at Oregon State University is developing non-viral vectors for gene therapy. We are located at the SW Waterfront of the Robertson Life Sciences Building in Portland, OR that houses scientists from OSU, OHSU and PSU. The current project aims to develop an inhalable nanotherapeutics that delivers messenger RNA for the treatment of cystic fibrosis, a monogenic disorder that primarily affects the lung. We are seeking a postdoctoral candidate with expertise in synthetic chemistry. The candidate will synthesize, characterize and develop novel materials for delivery of nucleic acids. A background in either synthetic chemistry, medicinal chemistry, polymer chemistry or lipid-based synthesis is a highly desirable. We are an interdisciplinary team and we support collaborations of the candidate with biologists, engineers and clinicians. Dr. Gaurav Sahay is committed for the career development of his team members and growth as independent scientists.
Synthesize and characterization of novel materials (cationic polymers or lipids) for nucleic acid delivery
Characterization of mRNA encapsulation, and other nanomaterial characterization.
Close collaborations with biologists and engineers that develop nebulized nanotherapeutics for mRNA delivery.
Work closely with undergraduates, postdocs, and graduate students in the lab.
10% Laboratory Maintenance:
Maintain lab equipment, Maintain online database of materials.
Assist in maintaining laboratory equipment and oversee lab safety and maintain lab safety as deemed necessary by the principal investigator.
5% Reports, Manuscript, & Proposal Preparation:
Maintain detailed records of data obtained in the laboratory. Prepare reports and manuscripts. Aid in proposal preparation.
- PhD in Chemistry, Chemical Engineering, Biomedical Engineering, Medicinal Chemistry, Organic Chemistry , or related discipline.
- Ability to effectively analyze data and communicate to others.
- Ability to communicate effectively to a variety of audiences in both written and spoken English.
- Ability to work effectively in a team environment.
- Experience with chemical synthesis and characterization
- This position is designated as a critical or security-sensitive position; therefore, the incumbent must successfully complete a criminal history check and be determined to be position qualified as per OSUStandard 576-055-0000 et seq. Incumbents are required to self-report convictions and those in youth programs may have additional criminal history checks every 24 months.
- Experience with synthetic chemistry is highly preferred
- Experience with chemical characterization FTIR, IR, HPLC, LC-MS etc)
- Strong background in chemistry, polymer chemistry, and /or lipid chemistry is required
- Knowledge of materials for nucleic acid delivery and nanomedicine is desirable but not required.
- A demonstrable commitment to promoting and enhancing diversity.