Sangamo BioSciences Inc.

Cell Engineering - Research Scientist

Sangamo Therapeutics France

VALBONNE, France

Department: Cell Engineering

Location: Sophia-Antipolis, FR

Start date: ASAP


JOB SUMMARY:  


The individual will be responsible for supporting the Director with designing and conducting experiments to develop edited CAR-Tregs for our immunology programs. She/he will: conduct experiments which may involve coordinating a complex experimental protocol; collaborate with the Director and the project/development team to design gene editing approaches and integrate results in the project; Develop, test, and evaluate new protocols and methods by remaining up to date on relevant new literature and transfer new protocols to the development team.


ESSENTIAL FUNCTIONS

  • Design research approaches involving gene editing of Tregs, including background research, experimental design and execution, problem-solving, and writing up for reports, patents and publications.
  • Develop new protocols; test and evaluate a variety of approaches.
  • Perform complex experiments and maintain detailed records of experiments and outcomes; analyze and interpret research data resulting from original procedures and methods.
  • Participate in the technical transfer of research approaches to the process development team.
  • Perform ongoing literature review to remain current with new procedures and related research; propose new research directions based on new advances discussed in literature.
  • Supervise a technician/assistant engineer.

 

EDUCATION, EXPERIENCE AND SKILLS

 

-         Required:

  • Ph.D in Biological Sciences and at least three years of research experiences related to gene editing, cell engineering, molecular and cellular biology, vectorology (AAV, lentivirus) and immunology.
  • Comprehensive understanding of biological sciences principles and expert level of knowledge and skills in field of science related to research projects.
  • Must be a self-motivated, adaptable, and able to work in an innovative and challenging scientific environment.
  • Strong organizational, collaborative, and time management skills.
  • Strong ability to write and communicate effectively.
  • Experience with softwares (Geneious, Snapgene, FlowJo, GraphPad, Illustrator)
  • Good publication record and excellent references

·        Fluent English required / French speaking is a plus

 

-         Preferred :

  • Solid background in gene and cell therapy.
  • Solid background in gene editing.
  • Experience with cell engineering.
  • Experience with next generation sequencing and data analysis.
  • Experience with vectorology (Lentivirus, AAV)

 

APPLICATION

Candidates should send the following documents to jobs.france@sangamo.com:

-         Cover letter, including a motivation statement (1 page)

-         Detailed CV, including a summary of candidate’s research experience, list of publications and communications

 

Sangamo is an equal opportunity employer

 

 


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Position

Cell Engineering - Research Scientist