Full Time Salary
£33,963 to £39,955 per annum (Discretionary range to £45,949), or £43,790 to £51,517 per annum (Discretionary range to £59,245) for the Senior level
Full time / Permanent
B24 is the soft X-ray tomography correlative cryo-microscopy beamline at Diamond.
The beamline uses full field cryo X-ray tomography to deliver 3D imaging to 25nm resolution of both native and fluorescent-labelled biological samples. Development of super resolution fluorescence microscopy is also active at the beamline in partnership with Micron at the University of Oxford. These and associated imaging techniques allow the visualisation of both the ultrastructure of cells and tissue as well as the chemical localisation of substructures and biomolecules and provide large-scale cellular context for further analysis.
B24 is part of the recently established Biological Cryo-Imaging group at Diamond which together with the capabilities of the physical science Imaging and Microscopy group provide a platform for using electrons, X-rays and visible light to image an array of samples across a diverse range of length and time scales.
We are now seeking an enthusiastic scientist with experience in X-ray imaging preferably as applied to biological samples. Suitable candidates will have expertise in beamline instrumentation, sample handling, data acquisition and analysis as well as a solid understanding of principles of X-ray imaging and a track-record in X-ray microscopy and related techniques. For appointment at the senior level experience in project management and/or a track record in development and commissioning of instrumentation is expected.
As a beamline scientist you will work closely with the Principal Beamline Scientist of B24 together with scientists, engineers and software groups in the imaging groups at Diamond to support the continued development and evolution of B24 including design, procurement, construction, commissioning of upgrades as well as ongoing user support. Future upgrade paths will look into new ways of sample delivery, use of phase contrast X-ray imaging and establishing robust correlative imaging workflows (correlative cryo-fluorescence and cryo-soft X-ray microscopy, cryo-CLXM and cryo-CLEM).
The beamline scientist will be expected to develop an internationally competitive research programme which exploits the capabilities of B24 and Diamond in general. You will have access to state-of-the-art laboratories for structural and cellular biology embedded at the beamline and within the Research Complex at Harwell to pursue your research. Diamond has a competitively funded PhD studentship programme and support for external grant funding through national and international funding agencies to take full advantage of the stimulating and exciting international research environment at Diamond is also provided.
Please make informal inquiries to Maria Harkiolaki (email@example.com).