Exscientia

Associate Director - Precision Medicine

Exscientia

Oxford, United Kingdom

Description

About Exscientia

Exscientia is an AI-driven pharmatech company committed to discovering, designing and developing the best possible drugs in the fastest and most effective manner. Exscientia developed the first-ever functional precision oncology platform to successfully guide treatment selection and improve patient outcomes in a prospective interventional clinical study, as well as to progress AI-designed small molecules into the clinical setting. Our pipeline demonstrates our ability to rapidly translate scientific concepts into precision-designed therapeutic candidates, with more than 25 projects underway. By designing better drugs, faster, we believe the best ideas of science can rapidly become the best medicines for patients.

In addition to that, we have pioneered the use of live primary human tissues as models to study the activity of anticancer drugs in a clinically relevant setting. In a groundbreaking study (Kornauth et al., Cancer Discovery 2021) it was shown that our approach could prioritize highly effective molecules for late-stage cancer patients. We apply this technology to target discovery, activity and mechanistic studies all the way to the identification of biomarkers. The Project Lead position is crucial to our continuous growth in this space.

You Will Have The Opportunity To:

  • Lead cutting-edge research projects at the interface of preclinical and clinical research. In particular:
    • Study the ability of drug activity measured in primary human tumour tissues using cutting-edge high content assays to predict clinical drug response.
    • Build a unique data asset consisting of phenotypic drug response, -omics and clinical annotation data that can be used for target and biomarker discovery.
  • Grow and coordinate a multidisciplinary team of wet lab scientists, bioinformaticians, software developers and clinical operations specialists working with experts and clinical partners across the globe.
  • Identify and implement process improvements ensuring continuous high quality of data generation.

Requirements

  • PhD in biomedical sciences (molecular biology, biochemistry, medicine or similar); postdoctoral training is a bonus.
  • At least 5 years of prior experience in industry or a quality managed academic environment.
  • Leadership of multidisciplinary project teams of 5-10 individuals at the interface of preclinical and clinical research.
  • Prior experience with handling and working with primary human tissues, development of high content imaging assays, working with high throughput screening and lab automation equipment or in clinical cancer research is a bonus.
  • You are an analytical, structured, pragmatic problem solver with attention to detail. You have excellent organisational and project management skills, excellent oral and written English communication skills and are and empathic leader who can motivate teams to achieve extraordinary results.

Benefits

  • Work together to make a positive contribution to patients by revolutionising the pharmaceutical industry through AI-driven discovery.
  • We will work with you to kick-start or further grow your career – from funding for professional development and conference attendance. To also ensuring you will have the opportunity to acquire valuable skills, work on problems that matter, and learn from world-class technical and scientific leaders.
  • Opportunity to join an inclusive, collaborative and intellectually stimulating culture
  • We will work with you to provide a highly competitive compensation as we continue to grow and thrive.
  • Our teams health and well-being is important to us which is why we provide wellbeing and mindfulness support.
  • We offer a generous holiday allowance, provide flexible working and remote working to encourage all of our team to manage their own work, time and life.
  • We offer daily lunch, regular team events and lots of opportunities for casual networking.
  • Hear from our team why they enjoy working here Click here

Please apply via recruiter’s website.