University of California Davis (UC Davis)

Assistant Project Scientist & Postdoctoral Researcher

University of California Davis (UC Davis)

Davis, CA, United States

Assistant Project Scientist

The Department of Molecular and Cellular Biology at the University of California, Davis invites applications for one Assistant Project Scientist in biochemistry and Structural biology.

POSITION DESCRIPTION:

The position will focus on the functional and structural characterization of molecular assemblies that promote biogenesis and polymerization tubulin dimers into microtubules and mechanisms of mitotic kinesin motor proteins. The candidate will design and perform experiments using molecular biology, protein expression, protein biochemistry techniques and cryo-EM. This position requires strong molecular biology, protein biochemistry and structural biology skills to successfully execute these experiments. Candidates are preferred to have demonstrated success in using structural biology approaches such as cryo-EM and/or x-ray crystallography. The candidate will then summarize data and assist with the preparation of figures and writing of manuscripts for publication, as well as assist in writing and reviewing grant proposals. The ideal candidate is a highly motivated, responsible individual with strong interpersonal, communication and time-management skills who works well both independently and as part of a team.

BASIC QUALIFICATIONS:

PhD and relevant postdoctoral training in molecular biology, protein biochemistry, structural biology or a related field with laboratory research experience reconstituting protein complexes in vitro. Must have experience with structural biology (either X-ray crystallography or cryo-EM and single particle image analysis) and be experienced with general cloning, biochemistry and protein purification. Must be able to keep a detailed laboratory notebook of experiments and procedures and data for publications, proposals, and/or presentations.

MINIMUM QUALIFICATIONS:

Scientific training and skill equivalent to graduate work in structural biology, biochemistry and molecular biology.

Expertise in x-ray crystallographic structure determination and/or cryo-electron microscopy and single particle image methods

Experience with molecular biology techniques including transformations, DNA extraction, PCR, electrophoresis, site-directed mutagenesis and DNA sequence analysis.

Experience with protein construct design and optimization for structural studies.

Experience with record keeping and data storage.

Experience with Adobe Illustrator, Microsoft Word and Excel.

PREFERRED QUALIFICATIONS:

Experience with protein-protein interaction studies.

Experience with mammalian and/or insect cell culture protein expression.

Experience writing and editing manuscripts.

SALARY RANGE: Step I-VI $57,400-$74,200 [100% annual], commensurate with qualifications and experience

TERM OF APPOINTMENT: Appointments may be made up to 100%.

CLOSING DATE: For full consideration, all application materials must be received by November 15, 2019.

The job will remain open for applicants until January 20, 2020.

For more information about the Department, please visit the website: http://www.mcb.ucdavis.edu.

  • TO APPLY: Qualified applicants should upload a curriculum vitae, cover letter, statement of research experience and contact information of three references submitted via this URL: https://recruit.ucdavis.edu/apply/JPF03095
  • QUESTIONS: Please direct questions to Jawdat Al-Bassam, jawdat@ucdavis.edu
  • The University of California, Davis commits to inclusion excellence by advancing equity, diversity and inclusion in all that we do. We are an Affirmative Action/Equal Opportunity employer, and particularly encourage applications from members of historically underrepresented racial/ethnic groups, women, individuals with disabilities, veterans, LGBTQ community members, and others who demonstrate the ability to help us achieve our vision of a diverse and inclusive community.
  • Under Federal law, the University of California may employ only individuals who are legally able to work in the United States as established by providing documents as specified in the Immigration Reform and Control Act of 1986. Certain UC Davis positions funded by federal contracts or sub-contracts require the selected candidate to pass an E-Verify check. More information is available http://www.uscis.gov/e-verify.
  • UC Davis is a smoke & tobacco-free campus (http://breathefree.ucdavis.edu/).

If you need accommodation due to a disability, please contact the recruiting department.



Postdoctoral Researcher

The Department of Molecular and Cellular Biology, University of California, Davis invites applications for one Postdoctoral Researcher in Molecular and Cellular Biology.

POSITION DESCRIPTION:

The postdoctoral scholar will work on a project focused the structural and mechanisms that regulate tubulin dimer biogenesis, regulators of tubulin polymerization and/or mitotic kinesin motor proteins. The Al-Bassam lab utilizes in vitro reconstitution, biochemistry, x-ray crystallography and cryo-electron microscopy as a powerful combination to dissect molecular mechanisms of these systems. We have a particular interest in determining structures of multi-subunit complexes and then we test functional mechanisms using in variety of approaches. The specific project to be pursued will be developed jointly by the candidate and PI upon hiring. Postdocs will be expected to be proficient in the molecular cloning of DNA, recombinant protein production using a variety of expression systems (bacteria, baculovirus, mammalian cells), expertise in structural biology methods such as x-ray crystallography or cryo-electron microscopy and single particle image analysis methods. Please see recently published research from the lab: https://www.ncbi.nlm.nih.gov/pubmed/?term=Al-Bassam+J. https://biology.ucdavis.edu/people/jawdat-al-bassam

BASIC QUALIFICATIONS:

The applicant must have a Ph.D. in chemistry, biochemistry, biophysics, cell biology, or related field, and must have proven productivity with at least one first author publication. In addition, the applicant should be proficient in molecular biology and/or biochemical protein purification and molecular reconstitution methods. The successful applicant will have experience with either: 1) in vitro reconstitution using purified multi-subunit/components assemblies and 2) Structural biology methods such as cryo-EM and single particle image analysis and/or x-ray crystallography.. The applicant should be attentive and reliable with various modes of communication (email, texts, Slack), and will have the motivation to pursue and drive a project independently. Candidates will be expected to apply for independent funding.

SALARY RANGE: $50,760-$61,308 [100% annual], commensurate with qualifications and experience.

POSITION AVAILABLE/CLOSING DATE: For full consideration, all application materials must be received by November 15, 2019.

The job will remain open for applicants until January 20, 2020.

TERM OF APPOINTMENT: This one-year appointment is based on the needs of the research project. Appointment may be extended upon satisfactory performance.

To Apply: Qualified applicants should upload submit a cover letter, curriculum vitae, and research plan, and contact information for three references via this URL:

https://recruit.ucdavis.edu/JPF03203

Questions: Please direct questions to: Dr. Jawdat Al-Bassam, jmalbassam@ucdavis.edu

For more information about the department, please visit the website: http://www.mcb.ucdavis.edu

The University of California, Davis commits to inclusion excellence by advancing equity, diversity and inclusion in all that we do. We are an Affirmative Action/Equal Opportunity employer, and particularly encourage applications from members of historically underrepresented racial/ethnic groups, women, individuals with disabilities, veterans, LGBTQ community members, and others who demonstrate the ability to help us achieve our vision of a diverse and inclusive community.

Under Federal law, the University of California may employ only individuals who are legally able to work in the United States as established by providing documents as specified in the Immigration Reform and Control Act of 1986. Certain UC Davis positions funded by federal contracts or sub-contracts require the selected candidate to pass an E-Verify check. More information is available http://www.uscis.gov/e-verify.

UC Davis is a smoke & tobacco-free campus (http://breathefree.ucdavis.edu/). If you need accommodation due to a disability, please contact the recruiting department.

Please apply via recruiter’s website.

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