We have an exciting opportunity for an enthusiastic Advanced Research Assistant to join our Cancer, Ageing and Somatic Mutation group.
About the Team/Research:
The Translational Cancer Genomics Team focuses on understanding the consequences of alterations in the DNA of cancer cells. We do this at scale using multiple approaches including drug sensitivity screens and whole-genome CRISPR-Cas9 screens in cancer cell models. Vulnerabilities within cancer cells, identified from the data generated, can then be exploited as novel drug targets or as genetic markers for patient selection.
You will support both research and development projects and mechanistic follow up studies led by post-doctoral fellows in the group. Currently the main focus is on the development of new protocols for organoid derivation, as part of the HCMI https://www.sanger.ac.uk/science/collaboration/human-cancer-model-initiative-hcmi) and optimizing CRISPR-Cas9 screening protocols. The role will also contribute to various larger scale projects in the wider Garnett group and other teams within the institute, by delivering defined research projects and assisting with the day to day management of laboratory facilities. You will work with a variety of cancer cell models including organoids and utilise a range of molecular biology techniques including cloning and western blotting. The role will require you to be adaptable and have excellent interpersonal and communication skills to co-ordinate tasks between team members and collaborators within the institute.
• BSc (or equivalent) in a biological science or equivalent experience.
• Experience in a working laboratory setting
• Ability to follow instructions/protocols accurately & efficiently.
• Ability to keep good scientific records
• Proven ability to work effectively within a team.
• Ability to keep good scientific records.
• Ability to work independently and organise own workload.
• Computer literate
• Demonstrable attention to detail.
• Excellent communication skills.
• Experience in mammalian cell culture.
• Experience with molecular biology techniques, particularly western blotting and cloning.
• Demonstrated ability to adapt to regularly changing priorities & workloads.
• Experience with organoid culture
• Previous experience in cancer cell biology
• Supervisory experience
Applications must include a CV and cover letter outlining your suitability for the position.
Closing Date: 10th March 2020
The Wellcome Sanger Institute is a world leading genomics research centre. We undertake large-scale research that forms the foundations of knowledge in biology and medicine. Our findings are used to improve health and to understand life on Earth. Find out more at www.sanger.ac.uk or follow us on Twitter, Facebook, LinkedIn, Youtube and on our Blog.
Set across 130 acres, just outside of Cambridge, The Sanger Institute is located on the stunning Wellcome Genome Campus. Home to some of the world’s foremost institutes and organisations in genomics and computational biology, committed to delivering life-changing science with the reach, scale, and creativity to solve some of humanity’s greatest challenges.
There’s an attractive benefits package on offer at the Genome Wellcome Campus. We appreciate the importance of achieving work-life balance and support this with a number of family and carer-friendly policies. Plus a flexible working policy for those who may wish to amend their working pattern or arrangement.
As well as the usual benefits you would expect, we go much further:
• 25 days annual leave (extra 1 day to a maximum of 30 days for every year you work)
• Auto-enrolment into a generous Group Defined Contribution Pension Scheme, with enhanced company contribution (for more information, see our Pensions page)
• Up to 2 days annual paid volunteering leave
• Up to 10 days paid Emergency Carers Leave per year
• Family friendly environment including options for flexible and part-time working, an on-site Workplace Nursery salary Sacrifice Schemes for pre-school children and Summer holiday club
• Life Assurance Cover and a Group Income Protection Scheme (if on a contract of 12 months or more)
• Enhanced maternity leave and parental leave
• Access to substantial number of courses and training events onsite
• Private Healthcare Scheme (after 6 months service)
• Eyecare and Dental payment plans
• Concessions and discounts from our corporate perks site
Being part of the Genome Wellcome Campus you will be part of the beautiful working environment with an impressive range of benefits, services and facilities also including:
• Free bus service to and from Campus, covering various routes around Cambridge, Saffron Walden and surrounding villages
• A car-share initiative
• Free parking
• A number of on-site venues where you can meet, eat and socialise with colleagues
• A thriving Sports and Social Club which provides members with subsidised access to a gym, tennis courts, sports hall, fitness classes and a vibrant social calendar of events
Find out more about our Genome Wellcome Campus.
We hold an Athena SWAN Bronze Award and will consider all individuals without discrimination and are committed to creating an inclusive environment for all employees, where everyone can thrive.