NUFFIELD DEPARTMENT OF ORTHOPAEDICS, RHEUMATOLOGY AND MUSCULOSKELETAL SCIENCES
Advanced Microscopy Specialist (144248)
Grade 7: Salary in the range £32,817 – £39,152 per annum
We are seeking an Advanced Microscopy Specialist to participate in a research project led by Dr Marco Fritzsche and Prof Michael Dustin as part of a collaboration between the Kennedy Institute of Rheumatology (KIR), the Weatherall Institute of Molecular Medicine – Human Immunology Unit (WIMM – HIU) and Micron Imaging Initiative at the University of Oxford. The major focus of this collaboration is the development and maintenance of the Extended-resolution total internal reflection fluorescence-structured illumination (eTIRF-SIM) microscope. This eTIRF-SIM technology was initially developed by Prof Dong Li in the group of Nobel Laureate Eric Betzig at HHMI Janelia Farm (USA). The goal is to use the eTIRF-SIM technology in the context of multiple biomedically-motivated projects throughout the KIR, thereby to establish this tool as a day-to-day technology within the Kennedy Imaging Facilities, and to offer the methodology Oxford-wide to new users less-experienced with this approach. It is expected that the post holder develops and pursues their own research project at the interface of biology and optical custom-built microscopy technology.
The post holder will work with Dr Fritzsche’s team to maintain the eTIRF-SIM microscope at the KIR, verify its performance, and provide technical support for users from the groups of Dr Fritzsche and Prof Dustin, the KIR, WIMM and Micron on a day to day basis. It is expected that the position will provide opportunities for the post holder to innovate and publish on further developments in microscopy technology and biological insights resulting from the experiments supported.
You will hold a PhD in any of the disciplines of life sciences. You will have expertise and publications in super-resolution microscopy. You will also possess expertise in optical design, microscope construction, laser alignment, and biological sample testing. A proven track-record of collaborative research with experience of experimental design, execution, and analysis is essential.
This is a full-time fixed-term appointment until 31st July 2021.
The closing date for applications is 12 noon on Monday 27th January 2020. You will be required to upload a supporting statement and CV as part of your online application.
To apply for this role and for further details, including the job description and selection criteria, please click on the link below: