SCT Platform Manager

CancerCare Manitoba, located in Winnipeg, Manitoba, Canada is a provincial agency which provides clinical and academic services and leadership for cancer control and the treatment of blood disorders. We invite applications for the position of:

SCT Platform Manager

CancerCare Manitoba Research Institute – MacCharles Site

Permanent - Full-time (1.0 EFT)

Competition# 293-22-761069505

Job Summary:

The CancerCare Manitoba Research Institute (CCMR) through the support of the CancerCare Manitoba Foundation is developing an innovative, single cell technologies (SCT) research platform that requires a Platform Manager, a Platform Technician and a CRISPR Technician. The SCT Platform will include state-of-the-art instrumentation enabling: 1) the isolation of single cells (BD Bioscience, FACSMelody); 2) the characterization of single cells (10X Genomics, Chromium Connect and X); 3) the quantitative phenotyping of single cells (Molecular Devices, ImageXpress HT.ai; Akoya Biosciences, PhenoCycler Fusion; BioTechne ProteinSimple, Jess); and 4) Cancer modelling (CRISPR Cas9 library).

The platform will be managed by a small team of dedicated personnel including an SCT Platform Director, an SCT Platform Manager (posted position), an SCT Platform Technician and a CRISPR Technician, who in consultation with the SCT Platform User Committee (comprised of Principal Investigators/Senior Scientists) will oversee the daily operations, maintenance, and sustainability of the technologies. Reporting to the SCT Platform Director, the SCT Platform Manager (posted position) will drive and participate in activities to ensure the proper operations/usage of the technologies by an array of users (frequent and sporadic), with an overarching goal of maintaining platform longevity through proper usage and the coordination of preventative maintenance visits. The SCT Platform Manager is expected to have and continue to build a strength in single cell biology and its application in quantitative studies and consult/support the development of experiments and grant applications of users and Senior Scientists. Through engagements with SCT Platform team and User Committee members, the SCT Platform manager is expected to develop a comprehensive training program that encompasses both conceptual (presentations) and technical (hands-on) training that includes the development and revision of standard operating procedures (SOPs). The Manager is also expected to maintain up-to-date knowledge of the technologies and their application in research, actively promote/advertise the platform to recruit new users, develop online scheduling/billing forms, organize, and participate in User Committee meetings and complete annual reports.

 Qualifications:

Required:

• Post graduate degree (MSc or PhD) in life sciences (preferably a cancer-related field), or other related scientific discipline
• Prior knowledge and experience in cellular imaging/microscopy and/or 10X Genomics platforms and/or Next Generation Sequencing
• Minimum 2 years of direct related experience
• Experience working with multi-disciplinary research teams
• Experience preparing scientific presentations/literature
• Experience with Microsoft Office Suite (Word; PowerPoint; Excel)
• Experience with Statistical Programs (e.g., Prism; SPSS; SAS; MATLab)
• Must have satisfactory employment record
• Must be legally able to work in Canada

To be determined on the interview process:

• Organizational skills, exceptional attention to detail with the ability to work independently and prioritize work
• Excellent interpersonal, verbal and written communication skills
• Ability to work quickly, accurately, and with decorum while under deadline pressure and continuous interruptions
• Willingness to learn and share (train) new technologies
• Ability to learn quickly and work on own initiative (highly motivated and self-starter)
• Ability to safeguard confidentiality
• Project and time management skills

 Preferred:

• Minimum five years work experience (e., knowledge and highly relevant/extensive experience) in cellular imaging/microscopy and/or 10X Genomics platforms and/or Next Generation Sequencing and/or CRISPR technologies. An equivalent of education and experience may be considered by CancerCare Manitoba
• Experience with quantitative single cell approaches and their application in cancer research
• Experience as a group/team leader
• Experience and willingness to function as an integral team member
• Highly effective communication skills with individuals ranging from lay public to scientific professionals
• Experience preparing scientific proposals or applications
• Experience with the technical and conceptual training of others with scientific instrumentation, preferably cellular imaging/microscopy, 10X Genomics or next generation sequencing
• Experience with bioinformatics as it relates to single cell analyses (e.g., 10X Genomics and next generation sequencing)

 Asset:

• Ability to speak French

 Salary: Non-Union (compensation based on qualifications)

Closing Date: March 3, 2023 

This position is subject to a Criminal Record Check, including Vulnerable Sector Search, an Adult Abuse Registry Check and a Child Abuse Registry Check. The successful candidate will be responsible for any service charges incurred.

CancerCare Manitoba is committed to developing inclusive, barrier-free recruitment processes and work environment. If you are contacted by CancerCare Manitoba regarding a job opportunity or testing, please advise if accommodation measures must be taken to enable you to apply and be assessed in a fair and equitable manner.