PHD Thesis

The position is suitable for part-time employment.

Our mission as research center: Discover personalized medical solutions for environmentally triggered diseases to promote a healthier society in a rapidly changing world.

The Paul Langerhans Institute Dresden (PLID) is a satellite institute of Helmholtz Munich at the University Hospital and Faculty of Medicine “Carl Gustav Carus” of TU Dresden and founding partner of the German Center for Diabetes Research (DZD e.V.), which is funded by the German Ministry for Education and Research (BMBF). The DZD itself combines experts from all areas of diabetes research, so that basic research, epidemiology, translational research and clinical application deeply interconnect. Research focus of the PLID is the production and protection of the pancreatic islet beta cells for the prevention and therapy of all forms of diabetes.

The research group of Prof. Stephan Speier investigates the role of beta cell mass and function at distinct stages of diabetes pathogenesis and aims to discover novel therapeutic targets for beta cell protection and recovery in type 1 and type 2 diabetes. A central aspect of our research is the translation of our findings into the human setting by utilizing novel platforms to study human pancreatic tissue and islets. In addition, we utilize our unique platforms to optimize alternative cell sources for the successful generation of cell replacement therapies for diabetes.

The research group of Prof. Stephan Speier is seeking for a highly motivated

PhD candidate for the study of sex-specific differences in the endocrine regulation of glucose homeostasis (f/m/x)101935

Part time, 25,35 h/week

Dresden

PhD

Your mission

• Working with animal models and human tissue samples in combination with live cell imaging, biochemical, histological and cell physiological approaches
• Isolation and transplantation of islets
• Processing and analysis of microscopic images
• Recording and analysis of hormone secretion in perifusion studies
• Conducting complex molecular, cell physiological and biochemical experiments

Your qualifications

• Master’s degree (or equivalent) in Physiology, Cell Biology, Biomedicine, or any related fields in biological and medical sciences
• Ideally expertise in the work with animal models, cell biology and/or physiology
• Ability to work independently, efficiently and goal-oriented
• Excellent knowledge of the English language

What we offer you

scientific training at HELENA Graduate School
flexible working hours & time off in lieu
30 days annual leave
career consultation
mobile work
company pension scheme With its location directly on the Elbe River, the Dresden site offers a special quality of life. The strategic embedding of the institute in the midst of university and non-university research institutes creates a vibrant and intellectual atmosphere.

This position also provides the opportunity for you to build specialist knowledge and collect significant professional experience, both of which will help advance your scientific career.

Remuneration and social benefits are based on the collective wage agreement for public-sector employees at federal level (EG 13 50% TV EntgO Bund). In addition, there is also the possibility of granting an allowance if the necessary conditions are fulfilled. The position is (initially) limited to three years, but under certain circumstances an extension can be arranged.

To promote diversity, we welcome applications from talented people regardless of gender, cultural background, nationality, ethnicity, sexual identity, physical abilities, religion and age. Qualified applicants with physical disabilities will be given preference.
If you have obtained a university degree abroad, we require further documents from you regarding the recognition of the degree. Please request the recognition as early as possible.

**Interested?**If you have further questions, simply contact Katja Pfriem, 0351 7963 6612, who will be happy to be of assistance.
**Helmholtz Zentrum München
Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)
Institute of Pancreatic Islet Research
DZD-Paul Langerhans Institute Dresden at TU Dresden Fetscherstr. 74

01307 Dresden**

Total E-Quality Award for excellent gender equality policy for women and men: Helmholtz Munich is particularly committed to promoting professional equality between women and men. It therefore aims to increase the proportion of the underrepresented sex in the respective field. Helmholtz Munich is part of the Helmholtz Association, Germany's largest scientific organization. Altogether 43.000 people currently work in its 18 scientific-technical and biological-medical research centers. The Association's annual budget amounts to around 5 billion Euros.

This research center is part of the Helmholtz Association of German Research Centers. With more than 42,000 employees and an annual budget of over € 5 billion, the Helmholtz Association is Germany's largest scientific organisation.