Charité - University Medicine Berlin

2 PostDocs - Systems Biology and Metabolism

Charité - Universitätsmedizin Berlin

Berlin, Germany

The Charité – Universitätsmedizin Berlin is a joint medical faculty, which serves both Freie Universität Berlin and Humboldt Universität zu Berlin. As one of the largest university hospitals in Europe with an important history, it plays a leading role in research, teaching and clinical care. The Charité university hospital has also made a name for itself as a modern business with certifications in the medical, clinical and management fields.

2 PostDocs – Systems Biology and Metabolism

FIELD OF APPLICATION: CC02, Institut für Biochemie

CAMPUS: Charité Campus Mitte

Brief description of field of application:
Located in the heart of Berlin, the Charité – Universitätsmedizin Berlin is one of Europe’s largest and most research-intensive medical faculties. The Ralser’s laboratory is world-renowned for its studies that understanding how cellular metabolism, the network of biochemical reactions in the cell, is regulated, how it evolved, and how it maintains functional integrity in the ever-changing environment the cell is exposed to. This research addresses fundamental problems in the life sciences, where knowledge about cellular metabolic systems is required to develop new therapeutics and to understand the molecular basis of disease.

Your area of responsibility:
We are looking for two enthusiastic postdoctoral scientists to join Prof. Markus Ralser’s laboratory at the Charitè – Universitätsmedizin Berlin, Institute for Biochemistry. We have developed mass-spectrometry based methods that can very effectively measure thousands of quantitative proteomes and found computational strategies to link these to cellular metabolism. We will now apply to them to understand how protein expression dynamics influence metabolism. We will screen proteomic changes in thousands of yeast strains as well as human samples, and link them to mechanistically understand the changes in metabolism and predict the phenotypes they create. We encourage the application of both postdocs with an experimental, analytical, as well as computational background. The daily work could be in systematic metabolism research, the biological application of machine learning, or ‘big data’ analysis. The post is, hence, ideal for someone with a computational or experimental background to get into the generation or analysis of large biological datasets, into the conduction of functional genomics experiments, and into the prediction of phenotypes from multi-omics data. The postholders will also be working closely with the recently established ‘Nationaler Forschungskern Massenspektrometrie’, in the generation and analysis of clinical proteomics data for medical and epidemiological studies.

Your profile:
- PhD, or Research Doctorate, in the basic sciences
- Productivity documented in published research articles or patents;
- Experienced in the handling or generation or analysis of large and systematic experiments
- Desirable are experimental skills in Microbiology and Biochemistry

Ref. no.: CC02-01.20
Start: 01.06.2020
Length of employment: 36 Months (with the possibility for extension and tenure)
Working time: 39 hrs./week
Pay scale: E13 acc. to collective agreement TVöD VKA – K
Employees are grouped into pay scales according to their qualifications and personal requirements. You can find our collective bargaining agreements (Tarifverträge) here:

Contact person:
For further information please contact Prof. Markus Ralser, Tel. +49 30 450 528141, E-Mail:

Please send your application, quoting the above reference number, by 28 May 2020 by E-Mail to:

Charité – Universitätsmedizin Berlin

More Information about Charité as your employer:

makes its human resources decisions based on suitability, competence and professional performance. At the same time, it strives to increase the percentage of women in management positions and takes this into consideration where candidates are equally qualified within the limits of what is legally possible. Applications from people with a migrant background are also explicitly welcome. Severely disabled applicants are given preferential consideration in the case of candidates with equal qualifications. An extended certificate of conduct must be submitted. Any travel expenses incurred cannot be reimbursed.

DATA PROTECTION NOTICE: Charité points out that personal data is stored and processed as part of the application process in different areas of Charité (e.g. faculty, staff committee, human resources department). Furthermore, the data may be transferred or processed within the group as well as in locations outside the group (e.g. authorities) to protect legitimate interests. By applying, you agree to our data protection regulations and terms of use, which you can find here:

Apply with CV and Cover Letter

Must be a .doc, .docx, or .pdf file and no larger than 1MBMust be a .doc, .docx, or .pdf file and no larger than 1MB

2 PostDocs - Systems Biology and Metabolism