University of Antwerp (UA)

15 ESR (PhD student) positions for the European Training Network in Safety Pharmacology - INSPIRE

University of Antwerp (UA)

Antwerpen, Belgium

INSPIRE (www.inspire-safety-pharmacology.eu) is looking for 15 Early Stage Researcher (ESR) – PhD students with the knowledge and enthusiasm to help the project make meaningful research breakthroughs. Selected candidates will enrol on PhD programmes and be employed for 36 months. Application deadline: before February 19, 2020 (12 pm – CET).

About INSPIRE

The vision of INSPIRE is to advance and “inspire” Safety Pharmacology by exploring new technological capabilities to addressing emerging cardiovascular safety concerns. Hereto, INSPIRE unites expertise from academic teams, technology-providers, pharmaceutical companies, regulators and hospitals to create a European training platform for 15 Early Stage Researchers (ESRs). Key innovative aspects of INSPIRE include: i) in vitro humanized cardiomyocytes assays, ii) unparalleled in vivo hardware/software solutions, iii) in silico predictions of haemodynamics, iv) mass spectroscopy imaging of drug exposure, v) exploration of mechanisms of late-onset CV toxicity, as observed in cardio-oncology, and vi) early integration of feedback from industry and regulators.
Overall, INSPIRE constitutes a multidisciplinary and intersectoral training programme with a balanced combination of hands-on research training, intersectoral secondments, local courses and network-wide events on scientific and transferable skills, enabling future R&I collaborations. Hence, INSPIRE will equip the future generation of SP scientists with a wide range of scientific knowledge and the ability to adapt to a dynamic industry.

Offered positions

  • ESR1: Development and validation of improved hiPSC CM assays to study cardiac safety (more details here)
  • ESR2: Development and validation of cardiomyocyte model as a predictive assay to assess functional and structural cardiac liabilities (more details here)
  • ESR3: Empowering predictivity and speed of hiPSC CM assays by machine learning approach (more details here)
  • ESR4: Development of novel telemetry implants with added 3D micro-GPS functionality (more details here)
  • ESR5: Extending NOTOCORD-SenseTM with behavioural analysers to enable neuro-cardiovascular assessment in a cloud-based architecture (more details here)
  • ESR6: Development of new algorithms and software to analyse and quantify social interactions and behaviour (more details here)
  • ESR7: Validation and use of novel telemetry implants with 3D micro-GPS functionality for integrated neuro-cardiovascular assessment (more details here)
  • ESR8: An in silico approach to monitor and predict haemodynamics during safety pharmacology studies (more details here)
  • ESR9: Development of mass spectrometry imaging tools to study drug distribution and associated tissue-specific effects (more details here)
  • ESR10: Measuring arterial stiffness at different scales: a new toolbox for safety pharmacology (more details here)
  • ESR11: New pre-clinical screens in safety pharmacology (more details here)
  • ESR12: Assessing the cardiovascular safety liabilities of growth factor inhibition (more details here)
  • ESR13: Development of novel strategies to mitigate cardio-toxicity and heart failure (more details here)
  • ESR14: Chemotherapy-induced functional myocardial alterations: is a HFpEF stage preceding HFrEF? (more details here)
  • ESR15: Personalized SP against drug-evoked proarrhythmia (more details here)

Tasks and responsibilities

  • Selected candidates will perform independently scientific research within a collaborative international research consortium (training network).
  • Selected candidates will deliver written reports of your research on a regular basis
  • Selected candidates will prepare a doctoral thesis on the topics proposed by INSPIRE (more details here).
  • Selected candidates will publish scientific articles related to the research project of the assignment.
  • Selected candidates will (may) support the valorization of research results into tangible deliverables.
  • Selected candidates will participate to scientific meetings and conferences to present their research to the scientific community.
  • Selected candidates will actively participate in outreach activities aimed to promote your scientific research to a wider audience.
  • Selected candidates will get in contact with the other members of this international consortium and will benefit from the tailored training programme.
  • Selected candidates will take part in the academic and industrial secondments

Profile & requirements

  • Applicants must hold a MSc or equivalent in the field of Medicine, Pharmaceutical Sciences, Mathematics, Computer Science, Physics, Engineering, Exact Sciences, Chemistry, Biochemistry, and other Life Sciences.
  • Applicants can be of any nationality, but have to comply with the “Mobility Rule (cf. infra)”.
  • Applicants must have an ability to understand and express themselves in both written and spoken English to a level that is sufficiently high for them to derive the full benefit from the network training.
  • Applicants must be eligible to enrol on a PhD programme at the host institution (or at a designated university, in case the host institution is a non-academic organisation).

Applicants must have the necessary academic skills and background to make the success of a doctoral degree.

H2020 MSCA Mobility Rule: researchers must not have resided or carried out their main activity (work, studies, etc.) in the country of the host organisation for more than 12 months in the 3 years immediately before the recruitment date. Compulsory national service, short stays such as holidays, and time spent as part of a procedure for obtaining refugee status are not taken into account.
Applicants must have the necessary academic skills and background to make the success of a doctoral degree.
H2020 MSCA Mobility Rule: researchers must not have resided or carried out their main activity (work, studies, etc.) in the country of the host organisation for more than 12 months in the 3 years immediately before the recruitment date. Compulsory national service, short stays such as holidays, and time spent as part of a procedure for obtaining refugee status are not taken into account.

Benefits

  • Full-time employment constract by the host organisation for 36 months.
  • A competitive salary plus allowances. Moreover, funding is available for technical and personal skills training and participation in international research events.
  • Benefit from the designed training programme offered by the host organisation and the INSPIRE consortium.
  • Participation in international secondments to other organisations within the INSPIRE network and in outreach activities targeted at a wide audience.

For addition information, please refer to the .Information note for Marie Skłodowska-Curie ITN fellows

Application

Interested candidates are invited to apply by filing in the application form via the button apply from recruiter.

For additional information

Paz Yáñez Murillo Email: paz.yanez@uantwerpen.be Phone: +32 3 265 27 02

Please apply via recruiter’s website.