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Postdoctoral Scientist in Radiopharmaceutical Development – Radiochemist / Radiopharmacist

Employer
German Cancer Research Center in the Helmholtz Association (DKFZ)
Location
Heidelberg, Baden-Württemberg (DE)
Salary
-
Closing date
24 Aug 2024
Website
https://www.dkfz.de/
View moreView less
Discipline
Biomedicine, Chemistry
Job Type
PhD Position
Employment - Hours
Full time
Duration
Fixed term
Qualification
PhD
Sector
Academia

Job Details

„Research for a life without cancer“ is our mission at the German Cancer Research Center. We investigate how cancer develops, identify cancer risk factors and look for new cancer prevention strategies. We develop new methods with which tumors can be diagnosed more precisely and cancer patients can be treated more successfully. Every contribution counts – whether in research, administration or infrastructure. This is what makes our daily work so meaningful and exciting.

The Junior Research Group Translational Radiotheranostics is seeking a

Postdoctoral Scientist in Radiopharmaceutical Development – Radiochemist / Radiopharmacist

Reference number: 2024-0238

  Your Tasks:

The ideal candidate is expected to pursue a highly innovative project at the frontiers of
interdisciplinary cancer research. As part of this project, you will be responsible for...

  • synthesis and characterization of novel diagnostic, therapeutic and theranostic ligands, pharmaceuticals, and biomolecules, particularly against breast cancer.
  • radiolabeling with alpha-, beta-, and gamma-emitters, evaluation of coordination properties and radiation-induced physicochemical effects.
  • performing in vitro evaluation of in-house produced radiolabeled compounds (e.g., binding and internalization assays), preferably alone or in a collaborative environment.
  • collaborating closely with (radio-)biologists for drug lead optimization.
  • writing scientific publications and grant applications independently or in collaboration with other researchers.
  • co-supervising students and colleagues.
  • scientific presentation of results in internal and external meetings, such as group meetings, conferences, workshops etc.

Your Profile:

  • PhD and master's degree in chemistry, biochemistry, medicinal chemistry or pharmaceutical sciences, ideally specialized in radiochemistry, radiopharmacy, metalorganic or complexation chemistry
  • Broad skills in synthetic organic chemistry and drug design, especially peptides, peptidomimetics and small molecules/organic ligands
  • Proficiency in analytical methods (e.g., NMR, MS, HPLC, TLC, Gamma-spectroscopy)
  • Extensive experience in radionuclide handling, radiolabeling techniques and radiopharmaceutical synthesis
  • Strong publication record in internationally acknowledged scientific journals
  • Effective communication and teamwork capability in multi-collaborative and interdisciplinary settings
  • You should be highly-motivated, with strong problem-solving skills and ability to work independently in accordance to global GLP standards.
  • You should be passionate about science and possess a strong drive to impact cancer research.
  • Strong scientific English language proficiencies is mandatory, with additional German ideal
  • Experience with cell culture, biological assays and small animals is of significant advantage, but not a prerequisite

We Offer:

  • Excellent framework conditions: state-of-the-art equipment and oppor­tunities for inter­national networking at the highest level
  • Remuneration according to TV-L incl. company pension scheme and capital-forming benefits
  • 30 days of vacation per year
  • Flexible working hours
  • Possibility of part-time work
  • Family-friendly working environ­ment
  • Sustainable travel to work: subsidized Germany job ticket
  • Our Corporate Health Manage­ment Program offers a holistic approach to your well-being
  • Develop your full potential: access to the DKFZ International Postdoc Program and DKFZ Career Service with targeted offers for your personal development to further develop your talents

 

Contact:
Martina Benesova
Telefon: +49 6221 42 5355

The position is initially limited to 2 years with the possibility of prolongation.

Are you interested?

Then become part of the DKFZ and join us in contributing to a life without cancer!

Apply now

We are convinced that an innovative research and working environment thrives on the diversity of its employees. Therefore, we welcome applications from talented people, regardless of gender, cultural background, nationality, ethnicity, sexual identity, physical ability, religion and age. People with severe disabilities are given preference if they have the same aptitude.

Notice: We are subject to the regulations of the Infection Protection Act (IfSG). Therefore, all our employees must provide proof of immunity against measles.

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Deutsches Krebsforschungszentrum | Im Neuenheimer Feld 280 | 69120 Heidelberg | www.dkfz.de

Company

 

About the German Cancer Research Center (DKFZ)

The German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) is Germany’s largest biomedical research institute and a member of the Helmholtz Association of German Research Centers. Over 3,200 staff members from 88 nations are dedicated to performing and driving cutting edge research for a life without cancer. Organized in more than 100 divisions and research groups, the focus of our 1,400 scientists is to unravel the causes and mechanisms of cancer development and progression, and to develop novel strategies for the diagnosis, early detection, prevention and treatment of cancer though innovative translational research.

Scientists at the DKFZ have received the most prestigious academic awards, including Prof. Harald zur Hausen, awarded the Nobel Prize in Physiology or Medicine in 2008 for his pioneering work on Human Papilloma Viruses (HPV),and Prof. Stefan Hell, who received the Nobel Prize in Chemistry for his research on super-resolution imaging.

The DKFZ core site is located in Heidelberg, the “City of Science”, which is considered one of the most beautiful cities in Germany with a highly international community: An estimated 56,000 of Heidelberg’s 160,000 inhabitants have an international background – many of whom are scientists or students.

 

Research Topics and Scientific Collaborations

The DKFZ is an international leader in a number of research areas including stem cell research, bioinformatics and systems biology, cancer genomics, neurooncology, pediatric oncology, cancer prevention, tumor immunology, virology, radiooncology and medical image analysis. The interdisciplinary and collaborative research environment at the DKFZ also results in excellent opportunities for computational and data scientists with interest in biomedical applications.

Research at the DKFZ is organized into six research programs:

On the mission for a life without cancer, the DKFZ collaborates with renowned clinical and research institutions at the local, national and international level. A key goal is to continuously strengthen translational research activities with the aim of sustainably advancing state-of-the-art clinical cancer research in Germany and thereby improving the treatment outcomes and quality of life of cancer patients. Together with University Hospital partners across Germany, the DKFZ established the National Centers for Tumor Diseases (NCT) as leading Comprehensive Cancer Centers in Germany, as well as the Hopp Childrens’ Tumor Center (KiTZ) in Heidelberg with a specific focus on pediatric oncology. Within the German Cancer Consortium for Translational Cancer Research (DKTK), research institutions and university hospitals at eight partner locations collaborate with the DKFZ, the core center of the DKTK, to speed up the transfer of successful cancer research into clinical practice. Furthermore, the HI-TRON in Mainz is a cooperative effort to make full use of the potential of individualized immunotherapy.

 

Training Programs and Career Development

Talent management and career development are central parts of DKFZ’s mission to maintain scientific excellence. The DKFZ places strong emphasis on the international recruitment and comprehensive training of excellent scientists, specifically welcoming diverse and international backgrounds.

Dedicated programs train young scientists and clinicians and prepare them for their next career step:

The DKFZ has developed programs to support the reconciliation of family and careers at all levels and international employees are supported by the International Staff Services in the planning, preparation and realization of their stay in Heidelberg.

 

Innovation Management

The DKFZ builds on strong Innovation Management to foster the development of innovative preventive, diagnostic and therapeutic products for maximum societal benefit. It facilitates technology transfer through licensing and support of spin-off companies. Recent examples include iOmx Therapeutics, Apogenix and mtm laboratories. The DKFZ also has strong collaborations with industry partners, such as Bayer Healthcare, Bosch, SAP and Siemens.

Company info
Telephone
+49 (0) 6221 420
Location
Im Neuenheimer Feld 280
Heidelberg
Baden-Württemberg
D-69120
DE

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