Master thesis - Pulmonary Cell Culture Models for allergen detection
- Employer
- Helmholtz Association of German Research Centres
- Location
- Germany
- Closing date
- 25 Sep 2024
View moreView less
- Discipline
- Life Science
- Job Type
- Internship
- Employment - Hours
- Full time
- Duration
- Fixed term
- Qualification
- Undergraduate
- Sector
- Academia
Job Details
Diploma & Master Thesis
Job description:Master thesis - Pulmonary Cell Culture Models for allergen detection
102483
Full time, close to full time
Munich
Home Office Options
We are Helmholtz Munich. In a rapidly changing world, we discover breakthrough solutions for better health.
Our research is focused within the areas of metabolic health/diabetes, environmental health, molecular targets and therapies, cell programming and repair, bioengineering, and computational health. We particularly excel in the fields of basic research, bioengineering, artificial intelligence, and technological development.
Through this research, we build the foundations for medical innovation. Together with our partners, we seek to accelerate the transfer of our research, so that laboratory ideas can reach society and improve people’s quality of life at the fastest rate possible.
This is what drives us. Why not join us and make a difference?
Helmholtz Munich and the University of Rostock (Chair for Analytical Chemistry) jointly conduct research in the independent cooperation group Comprehensive Molecular Analytics (CMA). One focus of our work is the investigation of ambient aerosols, their sources and the related health effects on humans. The well-equipped laboratories of CMA are located in Munich Sendling with very good connections via public transport.
We are seeking a highly motivated and talented master student (f/m/x) with biological knowledge.
You will work in an innovative, well-equipped and scientifically stimulating surrounding, where you will combine theory and practice to understand the human health effects of aerosols, using in vitro methods. During your thesis, you will build solid skills in in vitro toxicology, aerosol science, cell culture (air-liquid interface, mono- and co-culture models), fluorescent imaging and other cellular and molecular assays.
The aim of the project is to establish and validate an alveolar co-culture model and compare its sensitivity with a bronchial cell culture model for allergen detection in ambient air or occupational environment. For this purpose, both models will be exposed to a selection of respiratory sensitizers nebulized with a VITROCELL® CLOUD system. Cytotoxicity, cytokine release and immune cell activation will be then evaluated.
Prof. Matthias Tschöp (Dr. Med., Dr. hc.), CEO of Helmholtz Munich: "We believe that excellent research requires a range of different perspectives. Diverse teams reach better solutions and are more innovative in their research topics.
Establishing our Diversity Management Strategy demonstrates our commitment to ensuring an appreciative company culture based on mutual respect. We are also implementing diversity-sensitive processes throughout our whole organization."
Your tasks- Etablishment, execution, and evaluation of in vitro cell exposures at air-liquid interface
- Generation and evaluation of cellular and molecular data
- Master student in Biology / Biochemistry / Biomedical science or similar
- Basic knowledge and experience with cell culture and biological assays are required
- Interest in learning cellular and molecular toxicological methods
- Structured and independent working style and ability to work in a team
- Excellent spoken and written English language skills
Desirable qualifications
- Practical experience in mammalian cell culture practices
- Basic experience/knowledge in aerosol toxicology issues
- Interest in aerosol science field and in multidisciplinary experimental research
Since 2005, we hold the TOTAL E-QUALITY award for exemplary action in the sense of an equal-opportunity organizational culture.
Helmholtz Munich is actively committed to diversity and inclusion in practice and is sustainably committed to equality.
The Diversity Charter has set itself the goal of promoting diversity in the world of work. By signing the charter, we commit ourselves to create an appreciative working environment for all employees.
Expected starting date: October 2024 - January 2025. Precondition is an enrollment at the University during the preparation of the master thesis.
We are committed to promoting a culture of diversity and welcome applications from talented people regardless of gender, cultural background, nationality, ethnicity, sexual identity, physical abilities, religion or age. Qualified applicants with physical disabilities will be given preference. If you have obtained a university degree abroad, we will require further documents from you regarding the comparability of your degree. Please request the Statement of Comparability for Foreign Higher Education Qualifications as early as possible.
Interested in applying?If you have any questions, feel free to contact Mathilde Noémie Delaval, +49 89 3187 49277, who will be happy to help.
Your application should include
25.09.2024
We are Helmholtz Munich.Work and plan your career at Helmholtz MunichRead more
Helmholtz Munich
Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)
Comprehensive Molecular Analytics
Gmunder Straße 37
81379 München
This research center is part of the Helmholtz Association of German Research Centers. With more than 42,000 employees and an annual budget of over € 5 billion, the Helmholtz Association is Germany's largest scientific organisation.
Company
The Helmholtz Association contributes to solving major challenges to assure the future of our society. With more than 39,000 people on staff in 18 national research centres, the Helmholtz Association is Germany’s largest scientific organization. The name Helmholtz stands for concerted research in which networks form the key principle behind inquiring thought and action. Concerted research is efficient and flexible.
The profile of the Helmholtz Association
The Helmholtz Association performs cutting-edge research which contributes substantially to solving the grand challenges of science, society and industry. To succeed in meeting these responsibilities, Helmholtz concentrates its work in six research fields: Energy, Earth and Environment, Health, Key Technologies, Matter, as well as Aeronautics, Space and Transport. Within each of these fields, research programs are developed by our scientists and regularly evaluated by renowned international experts. Their evaluation forms the basis for the programme-oriented funding that is allocated to Helmholtz research. Within the six research fields, Helmholtz scientists cooperate with each other and with external partners – working across disciplinary, organizational and national borders.
Promoting young academics
Helmholtz scientists, a high-performance infrastructure and modern and efficient research management are the ingredients to the Helmholtz Association‘s success and global impact.
Promoting young researchers is a major priority for the Helmholtz Association. Its qualification schemes for young researchers are geared mainly towards PhD students, postdocs and young managers. The Helmholtz Association has set high standards for its talent management. Its strategy begins with targeted recruitment of highly qualified staff at all levels, followed by comprehensive support aimed at further developing their potential. Ensuring equal opportunities is an essential element in all talent management activities undertaken by the Helmholtz Association.
The Helmholtz Graduate Schools and Research Schools at almost all Helmholtz Centres provide doctoral students with the general and specific skills and training they need, as well as ample opportunity to network with other working groups. The period following a doctorate is decisive in determining the direction and success of a scientific career. For this reason, we are about to establish Career Centers for postdoctoral researchers in the Helmholtz centres and a mentoring programme for especially gifted PostDocs in order to foster career orientation. This equips young researchers with the skills they need to go on to head a Helmholtz Young Investigators Group, for example. As a Young Investigator Group leader, junior scientists can independently set up their own group to conduct research in their specialist field.
Within its talent management strategy, the Helmholtz Association pays special attention to the increased recruitment of talented female scientists both from Germany and abroad. To this end, there are currently two funding programs supporting this policy ‘Funding of first-time appointments of excellent women scientists (W2/W3)’ and ‘Funding to recruit top-level international women scientists (W3)’.
The increasing complexity of the content, structures and framework conditions of scientific work today requires researchers to organise their projects, their employees and, of course, themselves in a highly professional and effective way. In response to these demands, we have set up the Helmholtz Management Academy to provide junior leaders in science with professional management training. Furthermore, the Helmholtz network provides a platform for the alumni of the Helmholtz Management Academy and Mentoring programme to come together and share their experiences of leadership, career development and lifelong learning.
- Location
-
Berlin
Berlin
10178
DE
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