Development of a novel therapeutic approach for cystic fibrosis

The “Molecular therapeutic approaches for genetic diseases and cancer” team located in the Oncolille Institute is looking for a post-doctoral researcher for a 2-year contract. The postdoctoral researcher will work within a consortium funded by the Vaincre la mucovisdose association. The project aims to develop therapeutic solutions for patients suffering from genetic disease and in particular from cystic fibrosis linked to a nonsense mutation. The recruited person will work within the newly built Oncolille Institute, which has all the equipment to accomplish her/his project. This institute is located on the Lille University Hospital campus. She/he will be responsible for characterizing new molecules that correct nonsense mutations in different cellular and mouse models.

The desired profile is a post-doctoral researcher who is highly motivated to invest in this project and - with expertise in analyzing CFTR channel expression - with solid knowledge in molecular and cellular biology, particularly in aspects of RNA translation and metabolism - with experience in working with mice and qualification to carry out animal experimentation - organized, autonomous, hard-working person with team spirit. For more information or to apply fabrice.lejeune@inserm.fr (website: https://nonsense.univlille.fr/en/)

Starting date: October 2024