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Research Fellow in immune cell migration and chemotaxis

Employer
University College London (UCL)
Location
London, England
Salary
Negotiable
Closing date
3 Aug 2024

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Discipline
Life Science
Job Type
Researcher
Employment - Hours
Full time
Duration
Permanent
Qualification
PhD
Sector
Academia

Job Details

About us

Biosciences is one of the world's foremost centres for research and teaching in the biological sciences and one of the largest Divisions within UCL.

This is an exciting opportunity to join Robert Insall's group. The Insall lab use quantitative microscopy and molecular genetics, backed up with computational models, to explain why cells move.

About the role

The main purpose of this position is to understand the signals that direct immune cells' migration when they extravasate from blood vessels to tissues, guided by signals in the extracellular environment. As cells respond and migrate, they often inactivate these signals and may release additional, secondary attractants themselves, complicating experimental analysis.

To address this complexity, we seek a biologist to set up haematopoietic cell lines that will allow us to analyze these processes quantitatively. Duties include maintaining and generating new haematopoietic cell cultures, performing and developing microscopy-based assays to test these cells, and interacting with dry lab members to accommodate experimental results with models. We use established cell lines and may establish others, as appropriate. 3D microprinting and device design & manufacture may also be important. If appropriate for the candidate we will also train them in coding and computational modelling.

This role is an open-ended contract with a funding end date of 30/11/2026 in the first instance. The lab has multiple grants which may be extended.

Appointment at Grade 7 is dependent upon having been awarded a PhD; if this is not the case, initial appointment will be at Grade 6B (salary £37,332 - £39,980 per annum) with payment at Grade 7 being backdated to the date of final submission of the PhD Thesis.

This role is eligible for hybrid working with a minimum of 50-60% on site.

A job description and person specification can be accessed via the "Apply" button.

If you have any queries about the role, please contact Robert Insall. If you need reasonable adjustments or a more accessible format to apply for this job online or have any queries about the application process, please contact the Biosciences staffing team.

Job Ref: B02-07039

Closing Date: 04/08/2024 - 23:59 (UK time)

About you

You must have a Ph.D., equivalent qualification, or relevant subject area and proven experience and knowledge of cell biology, in particular live cell microscopy and/or molecular biology with cell lines.

Experience in microfabrication, or coding and/or familiarity with computational modelling would also be useful.

You will take part in the development, and delivery of research funded by the Wellcome Trust, generating novel insights into immune cell steering in vitro and in vivo. In addition to developing and conducting the research, you will communicate results as scientific preprints and papers and in scientific presentations at local, national, and international conferences.

What we offer

As well as the exciting opportunities this role presents, we also offer some great benefits. Please visit https://www.ucl.ac.uk/work-at-ucl/reward-and-benefits to find out more.

Our commitment to Equality, Diversity and Inclusion

As London's Global University, we are committed to equality of opportunity, to being fair and inclusive, and to being a place where we all belong. We therefore particularly encourage applications from candidates who are likely to be underrepresented in UCL's workforce.

Our division holds an Athena SWAN Silver award, in recognition of our commitment to advancing gender equality.

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