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PhD student Institute of Laboratory Medicine, Clinical Chemistry and Molecular diagnostics

Employer
Universität Leipzig, Medizinische Fakultät
Location
Leipzig, Sachsen (DE)
Salary
"-"
Closing date
4 Jun 2024

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Discipline
Biomedicine, Health Science
Job Type
PhD Position
Employment - Hours
Full time
Duration
Fixed term
Qualification
Masters
Sector
Academia

PhD student

Institute of Laboratory Medicine, Clinical Chemistry and Molecular diagnostics

Deadline for application: 30.04.2024

Hiring date: At the earliest possible date

Duration: 1 Year (with a possibility of extension)

Working time: 20 h per week

Two PhD student positions are available in the research group of Prof. Berend Isermann under the supervision of Dr. Shrey Kohli at the Institute of Laboratory Medicine at Leipzig University. The projects aim at studying the role coagulation proteases on the interaction between placenta (especially trophoblast cells), endothelial cells and immune system in the context of pregnancy complications (preeclampsia, IUGR, placental insufficiency). The main focus is to study cell-cell-interaction using in-vitro and in-vivo models and to determine the translational relevance of our results. Please also have a look at our publications to get an idea about our research interests: Kohli, Isermann, Blood 2021; Kohli, Isermann, Blood 2016; Ranjan, Isermann, Nature Commun 2017; Nazir, Isermann, Blood 2017; Madhusudhan, Isermann, Nature Commun 2015; Shahzad, Isermann; Kidney Int 2015.

The project involves:

  • Applying various cell culture methods to co-culture different cell types and to analyze maladaptative cellular communication during pregnancy and beyond. An interdisciplinary project studying the cellular interactions during pregnancy and its effect post-partum. Investigation of different genetically modifies mouse models. Collection and analysis of biomaterial from humans. Investigation of specific and novel molecular interactions in various in vivo disease conditions.

Requirements

  • Dedication to science, commitment to the work, open and communicative personality Successful completion of master's degree in life sciences (biology, biochemistry, biotechnology) Relevant research experience (preferably international) and fluent English communication skills Comprehensive detailed knowledge of immunophenotyping techniques such as FACS, knowledge in molecular biology, cell culture, mRNA, protein and DNA analysis, epigenetics and cloning techniques Comprehensive detailed knowledge in cell culture, cell migration, cell proliferation, co-culture models and cell death are required Knowledge in the field of developmental biology, the vascular system, placenta biology. Zeal for scientific writing and ability to write grant proposals, research articles.

As a public employer in the heart of Leipzig, we stand for a corporate culture in which cooperation for the best care of our patients is paramount. As a maximum provider with 27 clinics and about 4,000 employees, we provide groundbreaking technical specialization as well as state-of-the-art structural and technical infrastructure.

Please send your applications to: Shrey.Kohli@medizin.uni-leipzig.de.

By submitting your application, you agree that your personal data provided in the context of the application Data will be processed for the purpose of the application. The information on the collection and processing of personal data for applicants you will find here.

For information on the application process, please contact Dr. Shrey Kohli at 0049 341 / 97-22204 or Shrey.Kohli@medizin.uni-leipzig.de

Severely handicapped applicants are given preferential treatment if they are equally qualified. Please add appropriate evidence to your application.

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