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Postdoc (f/m/x) in Machine Learning in Biomedicine

Helmholtz Association of German Research Centres
Closing date
21 Apr 2024

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Job Type
Employment - Hours
Full time
Fixed term

Job Details

Area of research:

Scientific / postdoctoral posts

Job description:Postdoc (f/m/x) in Machine Learning in Biomedicine


Full time

Neuherberg near Munich

Home Office Options

We are Helmholtz Munich. In a rapidly changing world, we discover breakthrough solutions for better health.

Our research is focused within the areas of metabolic health/diabetes, environmental health, molecular targets and therapies, cell programming and repair, bioengineering, and computational health. We particularly excel in the fields of basic research, bioengineering, artificial intelligence, and technological development.

Through this research, we build the foundations for medical innovation. Together with our partners, we seek to accelerate the transfer of our research, so that laboratory ideas can reach society and improve people’s quality of life at the fastest rate possible.

This is what drives us. Why not join us and make a difference?

The Computational Health Center (CHC) is globally recognized for innovations in data analysis and modeling of biological systems and diseases, anchored at Helmholtz Munich and the Technical University Munich. The Theis Lab has a long-standing reputation for pioneering machine learning and AI methods in molecular biology, in particular on single-cell genomics and microscopy. The position is co-supervised by Joachim Schultze (DZNE, Bonn) and includes lab visits in Bonn.

Prof. Matthias Tschöp (Dr. Med., Dr. hc.), "We believe that excellent research requires a range of different perspectives. Diverse teams reach better solutions and are more innovative in their research topics.

Establishing our Diversity Management Strategy demonstrates our commitment to ensuring an appreciative company culture based on mutual respect. We are also implementing diversity-sensitive processes throughout our whole organization."

Your tasks

The role involves developing and applying decentralised machine learning/AI tools to analyse high-parameter flow cytometry and high-resolution single-cell multi-omics data for diagnostic purposes in a clinical multi-center study based on the Scanpy platform and Swarm Learning. The position is part of a national consortium about “Swarm Learning for precision medicine in infectious diseases and pandemic preparedness” including experts in the fields of data and information sciences, immunology, virology, clinical infectious diseases, and ethics.

It provides an opportunity for close collaboration with the Schultze Lab at the Department of Systems Medicine at the German Center for Neurodegenerative Diseases, along with the possibility of conducting longer research visits to Bonn. This innovative work sets a precedent for applying AI across medical disciplines. If you are enthusiastic about addressing critical questions in the field of AI in medicine and contributing to the progress of precision medicine, you are encouraged to apply for this postdoctoral position.

  • Develop a decentralised, automated machine learning approach to model clinical single-cell flow and multi-omics data for diagnostics based on deep representation learning and downstream attention-based supervised multiple instance learning.
  • Interpret trained model via attention and prior knowledge.
  • Develop a disease severity classifier for COVID-19 based on high-parameter cytometry data and integrate this with multimodal single cell omics samples.
  • Provide guidance and supervision of students.
Your profile
  • PhD in computer science, computational biology or related field.
  • Excellent skills in AI/ machine learning and applications thereof.
  • Strong programming/data engineering skills.
  • Background and/or strong interest in biomedical questions.
  • Excellent analytical, technical, and problem-solving skills.
  • Motivated team player with excellent communication and presentation skills, including experience in communicating across discipline boundaries.

Since 2005, we hold the TOTAL E-QUALITY award for exemplary action in the sense of an equal-opportunity organizational culture.

Helmholtz Munich is actively committed to diversity and inclusion in practice and is sustainably committed to equality.

The Diversity Charter has set itself the goal of promoting diversity in the world of work. By signing the charter, we commit ourselves to create an appreciative working environment for all employees.

If you fulfil all the requirements, you may be eligible for a salary grade of up to E 13. Social benefits are based on the Collective Wage Agreement for Public-Sector Employees (TVöD). The position has an (initial) fixed term of 2 years but may be extended under certain circumstances.

We are committed to promoting a culture of diversity and welcome applications from talented people regardless of gender, cultural background, nationality, ethnicity, sexual identity, physical abilities, religion or age. Qualified applicants with physical disabilities will be given preference.
If you have obtained a university degree abroad, we will require further documents from you regarding the comparability of your degree. Please request the Statement of Comparability for Foreign Higher Education Qualifications as early as possible.

Interested in applying?

If you have any questions, feel free to contact Dr. Anna Sacher, 089 3187-2926, who will be happy to help.

Your application should include

We are Helmholtz Munich.Why join us?

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Helmholtz Munich
Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)
Institute of Computational Biology
Ingolstädter Landstraße 1
85764 Neuherberg

This research center is part of the Helmholtz Association of German Research Centers. With more than 42,000 employees and an annual budget of over € 5 billion, the Helmholtz Association is Germany's largest scientific organisation.


The Helmholtz Association contributes to solving major challenges to assure the future of our society. With more than 39,000 people on staff in 18 national research centres, the Helmholtz Association is Germany’s largest scientific organization. The name Helmholtz stands for concerted research in which networks form the key principle behind inquiring thought and action. Concerted research is efficient and flexible.

The profile of the Helmholtz Association

The Helmholtz Association performs cutting-edge research which contributes substantially to solving the grand challenges of science, society and industry. To succeed in meeting these responsibilities, Helmholtz concentrates its work in six research fields: Energy, Earth and Environment, Health, Key Technologies, Matter, as well as Aeronautics, Space and Transport. Within each of these fields, research programs are developed by our scientists and regularly evaluated by renowned international experts. Their evaluation forms the basis for the programme-oriented funding that is allocated to Helmholtz research. Within the six research fields, Helmholtz scientists cooperate with each other and with external partners – working across disciplinary, organizational and national borders.

Promoting young academics

Helmholtz scientists, a high-performance infrastructure and modern and efficient research management are the ingredients to the Helmholtz Association‘s success and global impact.
Promoting young researchers is a major priority for the Helmholtz Association. Its qualification schemes for young researchers are geared mainly towards PhD students, postdocs and young managers. The Helmholtz Association has set high standards for its talent management. Its strategy begins with targeted recruitment of highly qualified staff at all levels, followed by comprehensive support aimed at further developing their potential. Ensuring equal opportunities is an essential element in all talent management activities undertaken by the Helmholtz Association.

The Helmholtz Graduate Schools and Research Schools at almost all Helmholtz Centres provide doctoral students with the general and specific skills and training they need, as well as ample opportunity to network with other working groups. The period following a doctorate is decisive in determining the direction and success of a scientific career. For this reason, we are about to establish Career Centers for postdoctoral researchers in the Helmholtz centres and a mentoring programme for especially gifted PostDocs in order to foster career orientation. This equips young researchers with the skills they need to go on to head a Helmholtz Young Investigators Group, for example. As a Young Investigator Group leader, junior scientists can independently set up their own group to conduct research in their specialist field.

Within its talent management strategy, the Helmholtz Association pays special attention to the increased recruitment of talented female scientists both from Germany and abroad. To this end, there are currently two funding programs supporting this policy Funding of first-time appointments of excellent women scientists (W2/W3)’ and ‘Funding to recruit top-level international women scientists (W3)’.

The increasing complexity of the content, structures and framework conditions of scientific work today requires researchers to organise their projects, their employees and, of course, themselves in a highly professional and effective way. In response to these demands, we have set up the Helmholtz Management Academy to provide junior leaders in science with professional management training. Furthermore, the Helmholtz network provides a platform for the alumni of the Helmholtz Management Academy and Mentoring programme to come together and share their experiences of leadership, career development and lifelong learning.

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