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Post-Doctoral Research Fellow

Employer
Fred Hutchinson Cancer Center
Location
Seattle, Washington State
Salary
$67,728 to $100,000
Closing date
21 Apr 2024

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Discipline
Biomedicine
Job Type
Postdoctoral
Employment - Hours
Full time
Duration
Permanent
Qualification
PhD
Sector
Charity/NGO

Job Details

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

 

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

 

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. These values are grounded in and expressed through the principles of diversity, equity and inclusion. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an anti-racist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, anti-racism and inclusion.

 

The Nabet laboratory is recruiting a highly motivated postdoctoral fellow to carry out research in the fields of targeted protein degradation and proximity-induced therapeutics. The goals of our research program are to develop strategies to target cancer drivers by controlling protein homeostasis to gain new biological insights into clinically relevant targets and to advance new therapeutic strategies in cancer. The Nabet laboratory develops and deploys innovative chemical biology technologies such as the dTAG system to rapidly eliminate target proteins for therapeutic target discovery and validation (Nabet et al., Nature Chemical Biology 2018; Nabet et al., Nature Communications 2020). The Nabet laboratory is highly collaborative and works extensively with medicinal chemists to develop inhibitors and degraders for cancer drug targets (Ferguson and Nabet et al., Nature Chemical Biology 2020; Li et al., European Journal of Medicinal Chemistry 2022). We are committed to supporting the next-generation of scientists and believe in collaborative science (Nabet, ChemBioChem 2021). This is an exceptional opportunity to join a new team that is pushing the boundaries of cancer chemical biology. 

 

Responsibilities

We are seeking candidates that will drive rigorous scientific projects utilizing state-of-the-art targeted degradation approaches including the dTAG system, chemical probes, genome-wide CRISPR knockout screens, molecular biology, biochemistry, next-generation sequencing, and in vivo murine modeling, with the goal of understanding the mechanisms of oncogenes in cancer and developing new therapeutic approaches. The position will require both independent research as well as the ability to collaborate closely with medicinal chemists, computational biologists, and other colleagues. 

 

Qualifications

Minimum Qualifications:

  • A recent PhD, and/or MD and a track record of independent productive research. Excellent written and verbal communication skills are required. A strong foundation in cell culture, genetic engineering, next-generation sequencing, murine modeling, molecular biology, biochemistry, and/or chemical biology is highly desirable. Fellowship opportunities are available through several philanthropic and government organizations and recruits who join the lab will be supported in their applications. 

 

Application instructions:

 

Please apply by submitting a CV, a brief description of past research experiences and future goals (not more than 1-2 pages), and contact information for three references.

 

The annual base salary range for this position is from $67,728 to $100,000 and pay offered will be based on experience and qualifications.  

This position may be eligible for relocation assistance. 

 

Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, life, disability, family life support, employee assistance program, onsite health clinic, income-based child care subsidy, tuition reimbursement, paid vacation (22 days per year), paid sick leave (up to 30 calendar days per occurrence of a qualifying reason), paid holidays (up to 13 days per year), and paid parental leave (up to 4 weeks).  

 

Company

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, our interdisciplinary teams of world-renowned scientists and humanitarians work together to prevent, diagnose and treat cancer, HIV/AIDS and other diseases. Our researchers, including three Nobel laureates, bring a relentless pursuit of, and passion for, health knowledge and hope to their work and the world. Together, our researchers are discovering new ways to detect cancers earlier, when cure rates are highest; developing effective treatments with fewer side effects; and learning how to prevent cancers from growing in the first place.

Our groundbreaking discoveries began in the 1970s with Dr. E. Donnall Thomas’s pioneering work in bone marrow transplantation, which led to him receiving the 1990 Nobel Prize in physiology or medicine. Since then, Hutch researchers have made a number of breakthroughs, including developing immunotherapies that use the immune system to defeat cancer and advancing the understanding of human biology. 

Admittedly, the eradication of cancer and other life-threatening diseases is an ambitious goal, one that demands tenacity, scientific excellence, collaboration and breakthrough creativity. To accomplish this, Fred Hutch attracts some of the world's greatest minds.

Our roster of internationally acclaimed scientists includes a MacArthur fellow, members of the National Academy of Sciences, members of the Institute of Medicine, members of the American Academy of Arts and Sciences, members of the American Association for the Advancement of Science and current and former Howard Hughes Medical Institute investigators.

Fred Hutch understands that disease research means more than searching for new treatments. We are home to the country's largest and oldest cancer prevention program, which has made key contributions to understanding how diet, exercise and other factors reduce the risk of acquiring the disease.

To accelerate our progress, we are part of the Fred Hutch / University of Washington Cancer Consortium. This research and clinical collaboration between the Hutch, the University of Washington, Seattle Children’s and Seattle Cancer Care Alliance enables our researchers to leverage each institution’s strengths and develop premier research programs across many types of disease. The Consortium is among 49 National Cancer Institute-designated comprehensive cancer centers nationwide.

Our Commitment to Diversity

We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We are proud to be an Equal Opportunity and VEVRAA Employer. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability, marital or veteran status, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to our Employee Services Center at escmail@fredhutch.org or by calling 206-667-4700.

Company info
Location
Seattle
WA
98109
United States

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