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Postdoctoral Researcher

National Heart, Lung, and Blood Institute (NHLBI)
Bethesda, Maryland (US)
Commensurate with qualifications
Closing date
2 Feb 2024

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Job Type
Employment - Hours
Full time

Epigenetics/Systems Biology Postdoctoral Researcher

Department of Health and Human Services

National Institutes of Health (NIH)

National Heart, Lung and Blood Institute



The National Heart, Lung, and Blood Institute (NHLBI), a major component of the National Institutes of Health (NIH), Department of Health and Human Services has an opening for an Epigenetics & Systems Biology postdoctoral researcher to study immune memory, cellular differentiation, and pathological conditions using genomics, epigenomics and systems biology approaches. Our laboratory has developed the ChIP-Seq, MNase-Seq, single-cell DNase-seq, scMNase-seq, ACT-seq, scChIC-seq, and Hi-TrAC techniques to analyze genome-wide distribution of chromatin modifications and DNA-binding factors (Cell, 2007, 2008, 2009, 2012; Nature 2015, 2018; Nature Methods 2018, 2019; Nature Comm. 2022; Immunity 2022, 2023). Using these powerful techniques, we are studying the contribution of two-dimensional and three-dimensional nuclear structure in cells. Future studies will investigate the function and regulation of epigenetic mechanisms and three-dimensional nuclear structure in normal development and diseases at a single-cell resolution, particularly in the immune system. The incumbent will focus on bench work or computation work or both depending on previous training and expertise. Opportunities for extensive collaborations with the research communities are available.


The ideal candidate must have a Ph.D. in Molecular Biology or Biochemistry or computational biology with a strong record of publication. The candidate must have received a Ph.D. within the past five years.


The candidate will be supported with an excellent intramural NIH fellowship in a stimulating and interactive research environment at NIH. Salary is commensurate with research experience and accomplishments.  Send curriculum vitae and names and addresses of three references to:


Keji Zhao, Ph.D.

NIH Distinguished Investigator

Chief, Laboratory of Epigenome Biology

Director, Systems Biology Center

Division of Intramural Research

National Hear Lung and Blood Institute, NIH

Bldg.10, Rm.7B05

9000 Rockville Pike, Bethesda

MD 20892-1674



DHHS/NIH is an Equal Opportunity Employer

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