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Postdoctoral Scientist - Ghiam Lab - Regenerative Medicine Institute Eye Program

Los Angeles, California
Closing date
17 Jan 2024

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Health Science
Job Type
Employment - Hours
Full time
Job Description

The Cedars-Sinai Regenerative Medicine Institute is looking for a Postdoctoral Scientist to join Dr. Ghiam's laboratory!

Under the direction of Mehrnoosh Saghizadeh Ghiam, PhD, associate professor of Biomedical Sciences at the Cedars-Sinai Board of Governors Regenerative Medicine Institute Eye Program, the Saghizadeh Ghiam Laboratory is focused on identifying specific molecular corneal defects associated with corneal pathological conditions, such as diabetes. The goal of the Saghizadeh Ghiam Lab is to understand the roles of microRNAs in both the differentiated epithelial and stem cells of normal and diabetic corneas as well as their roles in driving peripheral activation of limbal stem cells in normal and diseased corneas. To learn more, please visit: Saghizadeh Ghiam Research Lab | Cedars-Sinai (

Are you ready to be a part of breakthrough research?

The candidate will be assigned to a funded project investigating the mechanism of microRNAs in limbal epithelial stem cells in rescuing vision in human organ-cultured corneas for diseased corneas such diabetic and limbal stem cell deficiency. The work will involve the use of stem cells, tissue and organ-cultured cornea, transfection, luciferase assays, QPCR, histological and molecular analysis of samples with the overall goal of translation of the approach to the clinic. In order to conduct this research the incumbent should have a primary interest in regenerative medicine, experience in the fields of visual neuroscience and/or gene therapy research, technical aptitude in molecular biology, protein analysis, microscopy and histology. Working independently but in close cooperation and in consultation with the Principal Investigator and a Project Scientist, the Postdoc will perform routine and complex laboratory procedures throughout their training period. The incumbent may develop, adapt, and implement new research techniques and protocols and will analyze and interpret data.
Primary Job Duties and Responsibilities:
  • May assist in preparation of grant proposals, but is not responsible for generating grant funds.
  • May participate in publications and presentations as author or co-author.
  • Designs and performs experiments. Will keep appropriate experimental records and documentation and analyze the results with the P.I.
  • Participation in laboratory meetings, keeping a lab notebook, performing calculations, tabulating data, summarizing methods and results of related experiments and general lab maintenance will be required.
  • Analyzes, interprets, summarizes and compiles data.
  • Operates and maintains equipment and instruments.


  • Doctorate (MD, PhD, VMD, or DDS) in area directly related to field of research specialization.

Experience and Skills:
  • Highly motivated and works independently on research projects designed by a mentor (typically the PI) within area of specialization.
  • Acquires thorough technical and theoretical knowledge of research project and objectives during one to five (1-5) year post-doctoral appointment.
  • Ability to function efficiently and cooperatively with a team of faculty, research associates, technicians and students.
  • Demonstrated aptitude to perform experimental protocols and procedures, including detailed data collection, and analysis, and operation and maintenance of specialized equipment.
  • Knowledge of safety standards and maintenance of specialized equipment.
  • Scheduling flexibility including evening, weekend and holiday rotation commitment. Travel may be required.
  • Excellent written and oral communication skills are essential.

About Us

Cedars-Sinai is a leader in providing high-quality healthcare encompassing primary care, specialized medicine and research. Since 1902, Cedars-Sinai has evolved to meet the needs of one of the most diverse regions in the nation, setting standards in quality and innovative patient care, research, teaching and community service. Today, Cedars- Sinai is known for its national leadership in transforming healthcare for the benefit of patients. Cedars-Sinai impacts the future of healthcare by developing new approaches to treatment and educating tomorrow's health professionals. Additionally, Cedars-Sinai demonstrates a commitment to the community through programs that improve the health of its most vulnerable residents.

About the Team

Cedars-Sinai is one of the largest nonprofit academic medical centers in the U.S., with 886 licensed beds, 2,100 physicians, 2,800 nurses and thousands of other healthcare professionals and staff. Choose this if you want to work in a fast-paced environment that offers the highest level of care to people in the Los Angeles that need our care the most.

Req ID : HRC0863500F
Working Title : Postdoctoral Scientist - Ghiam Lab - Regenerative Medicine Institute Eye Program
Department : Research - RMI
Business Entity : Cedars-Sinai Medical Center
Job Category : Academic / Research
Job Specialty : Postdoctoral Scholar
Overtime Status : EXEMPT
Primary Shift : Day
Shift Duration : 8 hour
Base Pay : $64,500.00 - $93,600.00

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