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Postdoc in applied mathematics and data analysis

Employer
LCSB – Luxembourg Centre for Systems Biomedicine
Location
Luxembourg (LU)
Salary
81 072.84
Closing date
15 Oct 2023

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Discipline
Computing, Engineering, Mathematics, Physics
Job Type
Postdoctoral
Employment - Hours
Full time
Duration
Fixed term
Qualification
PhD
Sector
Academia

Job Details

The Luxembourg Centre for Systems Biomedicine (LCSB) is an interdisciplinary research centre of the University of Luxembourg. We conduct fundamental and translational research in the field of Systems Biology and Biomedicine – in the lab, in the clinic and in silico. We focus on neurodegenerative processes and are especially interested in Alzheimer’s and Parkinson’s disease and their contributing factors. 

The LCSB recruits talented scientists from various disciplines: computer scientists, mathematicians, biologists, chemists, engineers, physicists and clinicians from more than 50 countries currently work at the LCSB. We excel becausewe are truly interdisciplinary and together we contribute to science and society.

Your Role...

The Systems Control Group seeks a highly skilled Postdoctoral Research Associate. Postdocs are expected to interact with the rest of the group, especially with PhD students and support grant writing.

The open position in part of a JPND project, funded by FNR. The project aims to enhance the outcome of Deep Brain Stimulation (DBS) in Parkinson’s disease (PD) through the individualization and optimization of stimulation settings. Our vision is to replace the current practice of selecting stimulation pulse width, amplitude, and frequency by trial and error with a model-based patient- specific calculation. This will be achieved by incorporating insights from novel clinical studies into individualized mathematical models underpinning clinically relevant DBS programming tools. The consortium is composed of neurologists, electrical and control engineers, computer scientists, movement scientists, and neurosurgeons from four European countries.

Using arange of mathematical tools, this project aims to improve our understanding of how DBS affects the brain. It combines all available datasets in the project to create models capturing patient-specific and personalized brain dynamics before and after DBS stimulation. Models will capture stimulation at a wide range of frequencies, pulse widths and amplitudes across different contact configurations. Data includes EEG, peripheral sensors (such as accelerometers), LFPs and clinical data. Changing stimulation parameters will give us a nonlinear view of changes in brain connections. This will build new hypotheses on the effect of DBS stimulation on different areas of the brain and help us predict effective stimulation parameters.

More details can be found here

What we expect from you…

Hold a Ph.D. degree in (applied or theoretical) mathematics, theoretical physics, engineering, or computer science. Candidates must have a publication record in data analysis and machine learning. Experience in computational neuroscience is a plus. Excellent working knowledge of English is required.

Here’s what awaits you at the LCSB...

  • Excellent work environment with state-of-the-art infrastructure, laboratory and administrative support
  • Truly connected. We work together with hospitals and research institutes on a national and international level as well as industrial partners. Connection between science and society is very important to us. From our school lab – the Scienteens Lab – to the different outreach activities and collaborative partnerships with patient associations, we love to listen to society’s needs and share our passion for science
  • Be part of a multicultural team. At the LCSB we have more than 50 nationalities. Throughout the year, we organise team-building events, networking activities and more

Find out more about us!

In Short...

  • Contract type: Full contract for 1.5 years (with the possibility of renewal up to 5 years contingent on performance and availability of funding)
  • Work hours: Full Time 40.0 Hours per Week
  • Location: Belval
  • Job reference: UOL05297

The yearly gross salary for every Postdoctoral Researcher at the UL is EUR 79095 (full time)

How to apply...

Applications should contain the following documents:

  • A detailed Curriculum Vitae and a motivation letter that includes a description of how you would contribute to the project and research group. These two documents should be emailed to Sofia Pereira (sofia.pereira@uni.lu) in a single PDF. Use the job title and reference number mentioned above in the subject line of your email. If you receive an offer, you will also need to complete the online submission at the bottom
  • Please have at least three references email their confidential letters directly to Sofia Pereira (sofia.pereira@uni.lu) within two weeks after submitting the application. Without these references your application will not be processed

Early application is highly encouraged, as the applications will be processed upon reception. Please apply formally through the HR system. Applications by email will not be considered.

The University of Luxembourg embraces inclusion and diversity as key values. We are fully committed to removing any discriminatory barrier related to gender, and not only, in recruitment and career progression of our staff.

About the University of Luxembourg...

University of Luxembourg is an international research university with a distinctly multilingual and interdisciplinary character. The University was founded in 2003 and has more than 6,700 students and more than 2,000 employees from around the world. The University’s faculties and interdisciplinary centres focus on research in the areas of Computer Science andICT Security, Materials Science, European and International Law, Finance and Financial Innovation, Education, Contemporary and Digital History. In addition, the University focuses on cross-disciplinary research in the areas of Data Modelling and Simulation as well as Health and System Biomedicine. Times Higher Education ranks the University of Luxembourg #3 worldwide for its “international outlook,” #20 in the Young University Ranking 2021 and among the top 250 universities worldwide.

General information:

The Systems Control group, led by Prof. Jorge Goncalves, develops computational methods that extract valuable information from a wide range of molecular and clinical time-series data. Bringing together diverse backgrounds (e.g. mathematics, control systems, machine learning, engineering and physics), we engage this problem from different perspectives for broad-ranging applications in biomedicine, including neurodegenerative and cardiovascular diseases, mechanisms of circadian rhythms and stem cell differentiation. For more information, please visit our website.

For further information, please contact Jorge Goncalves (jorge.goncalves@uni.lu).

Company

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The Luxembourg Centre for Systems Biomedicine (LCSB) is an interdisciplinary research centre of the University of Luxembourg. We conduct fundamental and translational research in the field of Systems Biology and Biomedicine – in the lab, in the clinic and in silico. We focus on neurodegenerative processes and are especially interested in Alzheimer’s and Parkinson’s disease and their contributing factors. For over a decade, we have developed our expertise in several fields – from genetics to metaproteomics, from enzymology to immunology, from computational biology to cheminformatics – to tackle the growing issue represented by neurodegenerative diseases worldwide. We want to further our understanding of the human brain and improve care for patients in Luxembourg and beyond.

Interdisciplinarity is key

We strongly believe that complex problems can only be solved when the best minds from different disciplines and cultures come together and form a team. The LCSB recruits talented scientists from various disciplines: join the mix of computer scientists, mathematicians, biologists, chemists, engineers, physicists and clinicians from more than 50 countries. We excel because we are truly interdisciplinary and together we contribute to science and society.

Are you fascinated by the complexity of the brain? Do you want to decipher its mechanisms to better prevent and treat neurodegeneration? Do you strive for excellence and believe in interdisciplinary collaboration? 3x YES – then join our team!  

Excellent work environment

In the south of Luxembourg, close to neighbouring France, Belgium and Germany, new architecture and the country’s history combine into an innovative campus. Scientists find a state-of-the-art infrastructure that is constantly evolving. At the LCSB, six scientific platforms offer services to all our researchers. Be it imaging, omics, data science or animal models – we have experts and equipment in house.

Here, researchers can concentrate fully on their science: Lab support as well as administrative staff relieve LCSB’s scientists of many tasks. We also value our dynamic corporate company culture, so be prepared for teambuilding events, networking activities and more.

Every day at the LCSB and in Luxembourg is truly international. Our 250 staff have joined us from all around the world, creating a rich and multicultural environment. The LCSB actively encourages researchers to visit international conferences, to join European and global consortia, and of course to invite collaborators to Luxembourg!

Truly connected

The LCSB cooperates closely with hospitals and healthcare professionals. We receive invaluable input from medical doctors and clinical researchers in many fields like neurology, pathology and neurosurgery. Their contribution is essential for the development of interventional therapies or new biomarker-based diagnostic tools and for testing their effectiveness in the clinic. 

We have established strategic partnerships with leading biomedical laboratories worldwide and with all major biological and medical research units in Luxembourg. The LCSB fosters collaboration with industrial partners as well and promotes the translation of fundamental research results into clinical applications.

The connection between science and society is very important to us. From our school lab – the Scienteens Lab – to the different outreach activities and collaborative partnerships with patient associations, we love to listen to society’s needs and share our passion for science. Research at the LCSB is truly connected in many different ways.

LCSB, the place to be for your PhD 

 

We teach interdisciplinarity to the young generations of scientists from day one. Most PhD students are part of Doctoral Training Units: groups of students from diverse fields, all working together on an overarching research topic.

Thanks to a high ratio of academics and post-docs to doctoral candidates, PhD students can benefit from supervision of our internationally recognised experts and additional guidance from colleagues with various levels of experience. Besides high-quality research training, the Doctoral School of Science and Engineering offers complementary training to complete knowledge and skills required for their career development.

The learning doesn’t stop there: pick one of the University’s many free science and soft skill courses, learn a new language or join the free university sports and arts program!

Outstanding Benefits

The university offers a competitive salary package, over six weeks of paid leave and 11 days of public holidays. Family is important to us: staff members can benefit from maternity and parental leave, plus 40 hours of personal time off each year to facilitate private appointments when needed. Luxembourg provides free public schools (including several public international schools) and after-school care as well as subsidised day care for smaller children.

You also benefit from top-notch health insurance. Every university employee is automatically enrolled in the national health scheme (CNS), offering coverage in Luxembourg and in the EU. You will also benefit from travel insurance both for your personal and professional trips. Public transportation is free in Luxembourg!

The university offers some subsidised housing units for doctoral researchers. You also receive meal vouchers and a discount on your meals at university restaurants.

o  More info about the LCSB and its research groups here

o  Find all career opportunities at the LCSB here

About the University of Luxembourg

The University of Luxembourg aspires to become one of Europe’s most highly regarded universities, with a distinctly international and interdisciplinary character.

Its core asset is its well-connected and world-class academic staff. It is known for its research and teaching in targeted areas such as Biomedicine, Data Science and Physics. The university strives to attract creative students and talented young researchers who will help us shape our future.

About biomedical research in Luxembourg

Luxembourg has made research & innovation one of the cornerstones of the nation’s vision for the future. The country has drawn up a national research strategy, built excellent facilities and gained high international recognition in specific domains such as biomedicine and healthcare. The country has the ambition to be a pioneer in implementing cutting-edge health technologies and strives to be among the leading countries in the world in the field of personalised data-driven medicine. Hospitals, public research institutes and the university work hand in hand to speed up the development of more effective preventive and diagnostic tools as well as better and safer treatments for patients. The LCSB, as part of the university, is a driver within this bustling biomedical network.

More information about research in Luxembourg on the Research Luxembourg and EURAXESS websites.

Company info
Website
Location
Esch-sur-Alzette
L-4362
Luxembourg

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