Technician/Senior Technician - Giustacchini Group

APPLICATION CLOSING DATE:  30th of June 2023

We are looking for a Research Technician to join the Giustacchini group at the Population and Medical Genomics Program at Human Technopole (HT). Our lab combines stem cell biology and functional genomics to understand malignant hematopoiesis and develop novel therapeutic strategies.

We are looking for an enthusiastic researcher who will lead the development of new in vitro assays to study the crosstalk between leukemia and its immune microenvironment. The successful candidate will also provide technical support to the projects of other researchers in the lab as well as help with general lab management.

The successful candidate will report to Alice Giustacchini, Research Group Leader of the Population and Medical Genomics Research Centre.

(S)He will have the following main responsibilities:

• Conducting experiments in human cell biology and functional genomics, with a strong emphasis on development, optimization and application of in vitro assays probing stem cells and immune cell functions.
• Applying, generating, and optimizing protocols for cell isolation and culture conditions.
• Applying, generating, and optimizing protocols for Flow Cytometry readout.
• Generating reliable data for publication in the projects to which they are assigned and record all data and results in specified forms (paper and electronic).
• Providing technical support and supervision to other laboratory members, including introduction and teaching of new laboratory techniques and support on the use of lab equipment to lab members.
• Liaising with the Centre’s Lab Manager and other staff to write risk assessments and ensure that they are regularly updated.
• Ensuring that all tissue culture users work according to health and safety guidelines and regulations.
• Participating in key aspects of general lab management and organization (e.g., managing inventories and stocks of samples, reagents, equipment, and materials.

Job requirements

Essential: 

• University degree; 
• Fluency in English 
• Experience in molecular biology, such as DNA/RNA manipulation, cloning and PCR; 
• At least two expertise selected from below:                                                                                                           -  Experience with the application of cutting-edge methods in molecular biology;                                                 -  Cell biology and genomics technologies, including human cell culture;                                                             -  Experience with handling human blood material and immune cell culture;                                                         -  Experience in flow cytometry and cell sorting. 

Preferential: 

• Experience with additional genomic techniques such as functional genomics library preparation (e.g. sc-RNA-seq), knockdown experiments (e.g. CRISPR/Cas9 genome editing, siRNA, shRNA). 

Required personal skills: 

• Ability to manage competing priorities in a fast-paced environment and to work independently; 
• Ability to build trust through operating with transparency and creating an open and positive environment; 
• Ability to work in a multi-cultural, multi-ethnic environment with sensitivity and respect for diversity. 

Special consideration will be given to candidates who are part of the protected categories list, according to L. 68/99 

Application Instructions: 

• CV  
• A motivation letter 
• Names and contacts of 2 referees 

Additional information 

HT offers a highly collaborative, international culture to foster top quality, interdisciplinary research by promoting a vibrant environment consisting of independent research groups with access to outstanding graduate students, postdoctoral fellows and core facilities. 

HT is an inclusive employer that fosters diversity and engages systematically to ensure that equal employment opportunities are provided without regard to age, race, creed, religion, sex, disability, medical condition, sexual orientation, gender identity or expression, national or ethnic origin or any other legally recognized status entitled to protection under applicable laws. 
HT offers attractive conditions and benefits appropriate to a leading, internationally competitive, research organization that promotes a collegial and open atmosphere. The compensation package granted will be internationally competitive and comprise pension scheme, medical and other social benefits. Candidates coming to Italy for the first time, or returning after residing abroad, benefit from very attractive income tax benefits. 

Number of positions offered: 1 

Contract offered: CCNL Chimico Farmaceutico, -fixed-term,  5 years, Employee level 
 

The role is based in Milan.