Research Specialist I - Dulac Lab

The Howard Hughes Medical Institute (HHMI) advances the discovery and sharing of scientific knowledge to benefit us all. As a biomedical research organization and philanthropy, HHMI supports a vibrant community of academic researchers, educators, students, and professionals. Together, we’re unlocking the fundamentals of biology and building an open, inclusive future for science.

The Dulac lab at Harvard University focuses on molecular, genetic and optical techniques to explore the molecular and neuronal basis of innate social behaviors in the mouse. We have an opening for a Research Specialist to join the team – this position will include technical support and experimental work for projects involving molecular and functional characterization of multiple neuronal circuits involved in social behaviors and neuronal reconstruction of images acquired via electron microscopy. More information about the team and their research can be found on the lab’s website: https://www.dulaclab.com/

About the Senior Research Technician role:
We are seeking a highly motivated individual to provide comprehensive technical support and experimental work for projects involving molecular and functional characterization of neuronal circuits, as well as correlated light and electron microscopy. The projects in our group will provide the opportunity to gain experience with multiple, interdisciplinary techniques, including mouse behavioral assays, fluorescent microscopy, transcriptomics and electron microscopy. As this work exists at the interface of molecular biology, microscopy and neuroscience, applicants with a varied background in training and education will be considered.

What we provide:

• A competitive compensation package with comprehensive health and welfare benefits.

• An opportunity to broaden research experience in a collaborative environment.

• A team that believes in mentorship and learning.

• Professional and educational development opportunities.

• A vibrant and inclusive lab and research community.

What you’ll do:

• Perform a variety of histological, molecular, and behavioral approaches and analyses to characterize neuronal circuit identity and function.

• Assist with experimental design, establishing new protocols, and setting up lab space and equipment.

• Perform experiments involving the harvesting and preservation of mouse tissue, thin tissue section slicing, and RNA/protein detection.

• Perform DNA extraction and PCR from isolated mouse tissue to determine animal genotype.

• Perform experiments involving processing of samples for electron microscopy, including tissue slicing, fluorescent confocal microscopy, silicon wafer processing, and image acquisition.

• Perform annotation of acquired electron microscopy images by tracing continuous neuronal processes.

• Collect and record data from experiments; process, organize, and summarize data.

• Instruct others in basic laboratory techniques.

• The successful candidate will perform tasks related to the research project independently while under the guidance and mentorship of the supervisor.

What you bring:

• A bachelor’s degree in biology, molecular biology, neuroscience, or a related field.

• Background training and knowledge of molecular biology and/or neuroscience.

• Basic knowledge of general laboratory practices and procedures is required.

• At least one year of laboratory research experience is strongly preferred.

• Experience in neuroscience and/or microscopy is preferred.

• Hands on experience with rodents is preferred.

• Knowledge of basic computer technologies, including specific software applications such as Windows system, MATLAB, and Python.

• Strong interpersonal skills, in addition to the ability to work both independently and as part of an interdisciplinary team.

• Must be well-organized with attention to detail, both experimentally and with communication.

• Must be self-motivated with excellent time management, organizational, and interpersonal skills.

Please include a cover letter detailing your interest in this position as part of your application.

Physical Requirements

Remaining in a normal seated or standing position for extended periods of time; reaching and grasping by extending hand(s) or arm(s); dexterity to manipulate objects with fingers, for example using a keyboard; communication skills using the spoken word; ability to see and hear within normal parameters; ability to move about workspace. The position requires mobility, including the ability to move materials weighing up to several pounds (such as a laptop computer or tablet). Work may involve possible exposure to malodorous vapors, low dose radiation, contamination by toxic chemicals and acids and presence of carcinogenic substances or other hazardous materials.

Persons with disabilities may be able to perform the essential duties of this position with reasonable accommodation. Requests for reasonable accommodation will be evaluated on an individual basis.

Please Note:

This job description sets forth the job’s principal duties, responsibilities, and requirements; it should not be construed as an exhaustive statement, however.  Unless they begin with the word “may,” the Essential Duties and Responsibilities described above are “essential functions” of the job, as defined by the Americans with Disabilities Act.