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Genome Editing and Therapeutics - Faculty – Center for Disease Neurogenomics – Manhattan, NY

Icahn School of Medicine at Mount Sinai
New York City, New York (US)
Closing date
2 Jul 2023

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Job Type
Faculty Member
Employment - Hours
Full time

Faculty recruitment in Genome Editing and Therapeutics at Center for Disease Neurogenomics (CDN) at the Icahn School of Medicine at Mount Sinai in New York City.

We are inviting applications for tenure-track faculty position (Assistant and Associate Professor level) for scientists that are working to develop the next generation of genome editing techniques and RNA and DNA-based therapeutics. 

This includes biomedical engineers, bioengineers, developmental biologists and molecular and cellular biologists that apply state-of-the-art approaches for new nucleic acid delivery technologies, such as CRISPR gene and base editing tools and oligonucleotide therapeutics, and approaches for more sophisticated control of transgene expression. We are looking for scientists that apply this emerging technology to human neurons and organoids, with the objective of discovering novel genes critical in neuronal maturation and function, and/or developing multiplexed approaches to evaluate the combinatorial interactions between the hundreds of genetic variants underlying neuropsychiatric disease risk. Next generation human genome editing and forward genetic neuronal screens will allow members of CDN to resolve the interactions
between genetic variants, cell types and molecular functions within an enhanced disease-relevant context.

The Center for Disease Neurogenomics is a hub of neurogenomics and disease biology, towards development and enhancement of precision medicine across neuropsychiatric disorders. The candidate will join anoutstanding team of scientists with world class expertise in a broad range of disciplines, including genetics and genomics, neuroscience and clinical psychiatry. The CDN philosophy is highly geared towards collaboration, inclusion, and cross-disciplinary interactions, particularly between basic wet lab and dry lab scientists and
clinicians, and we provide strong support to junior scientists.

The Center for Disease Neurogenomics is part of the Mount Sinai Health Care System, which is one of largest hospital systems in the United States, and the Icahn School of Medicine, which includes outstanding departments in psychiatry, neuroscience, genetics, immunology, stem cell biology, and experimental therapeutics, and over 5,000 faculty. The highly integrated structure of Mount Sinai’s departments, institutes
and clinical divisions provide a unique environment for scientific and medical collaborations that foster an ideal atmosphere for innovations aimed at addressing 21st century biomedical challenges. Mount Sinai is ranked as one of the nation’s top biomedical institutions in research, patient care, and education, and over the last 10 years has become a leader in biomedical data science. In addition to the CDN, faculty recruits will be appointed in the Departments of Psychiatry, Genetics and Genomic Sciences and Neuroscience, which are among the top 5 ranked departments in the USA based on NIH funding.

Applicants should hold a Ph.D., M.D. or M.D./Ph.D. and are expected to develop independent research programs. Candidates for the Associate Professor ranks must have a distinguished record of published research, demonstrating significant impact on the profession, and success at securing funding to support research programs. We offer highly competitive recruitment packages, strong institutional commitments to
faculty support, comprehensive benefits, relocation services, and a rewarding work and life environment. The Icahn School of Medicine at Mount Sinai is located in the heart of Manhattan, one block from Central Park.

Compensation range from 165K to 200K (not including bonuses / incentive compensation or benefits).

Salary Disclosure Information:
Mount Sinai Health System provides a salary range to comply with the New York City law on Salary Transparency in Job Advertisements. Actual salaries depend on a variety of factors, including experience, specialties, historical productivity, historical collections, and hospital/community need. As such, an actual salary may fall closer to one or the other end of the range, and in certain circumstances, may wind up being outside of the listed salary range. The salary range listed is for full-time employment and does not include bonuses / incentive compensation or benefits. 

About the Mount Sinai Health System:
The Mount Sinai Health System is New York City's largest academic medical system, encompassing eight hospitals, a leading medical school, and a vast network of ambulatory practices throughout the greater New York region. Mount Sinai advances medicine and health through unrivaled education and translational research and discovery to deliver care that is the safest, highest-quality, most accessible and equitable, and the best value of any health system in the nation. The Health System includes approximately 7,300 primary and specialty care physicians; 13 joint-venture ambulatory surgery centers; more than 415 ambulatory practices throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and more than 30 affiliated community health centers. The Mount Sinai Hospital is ranked on U.S. News & World Report's "Honor Roll" of the top 20 U.S. hospitals and is top in the nation by specialty: No. 1 in Geriatrics and top 20 in Cardiology/Heart Surgery, Diabetes/Endocrinology, Gastroenterology/GI Surgery, Neurology/Neurosurgery, Orthopedics, ENT, Pulmonology/Lung Surgery, Rehabilitation, and Urology. New York Eye and Ear Infirmary of Mount Sinai is ranked No. 12 in Ophthalmology. Mount Sinai Kravis Children's Hospital is ranked in U.S. News & World Report’s “Best Children’s Hospitals” among the country’s best in four out of 10 pediatric specialties. The Icahn School of Medicine is one of three medical schools that have earned distinction by multiple indicators: ranked in the top 20 by U.S. News & World Report's "Best Medical Schools," aligned with a U.S. News & World Report "Honor Roll" Hospital, and No. 14 in the nation for National Institutes of Health funding. Newsweek’s “The World’s Best Smart Hospitals” ranks The Mount Sinai Hospital as No. 1 in New York and in the top five globally, and Mount Sinai Morningside in the top 20 globally. For more information, visit or find Mount Sinai on Facebook, Twitter and YouTube.
The Mount Sinai Health System is an equal opportunity employer. We comply with applicable Federal civil rights laws and does not discriminate, exclude, or treat people differently on the basis of race, color, national origin, age, religion, disability, sex, sexual orientation, gender identity, or gender expression. 

Please specify Job Title of interest and send CV with Cover Letter to:
Alex Cano
Executive Director Physician Recruitment
Mount Sinai Health System

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