Senior Research Scientist, Rectal, Colon and Anal Cancer Biology

Colorectal Cancer Research Center | Smith Laboratory @MSK

Memorial Sloan Kettering Cancer Center, New York, NY

Memorial Sloan Kettering Cancer Center (MSK) is one of the world’s premier cancer centers, committed to exceptional patient care, leading-edge research, and superb educational programs. The blending of research with patient care is at the heart of everything we do. The institution is a comprehensive cancer center whose purposes are the treatment and control of cancer, the advancement of biomedical knowledge through laboratory and clinical research, and the training of scientists, physicians and other health care workers.

The Smith laboratory, an NCI-funded research program, in conjunction with the Surgery Department for Rectal Cancer Research, is searching for an outstanding scientist with a strong interest in translational research focused on the biology of rectal, colon, and anal cancer. The Smith laboratory focuses on improving response to neoadjuvant therapies for patients with rectal cancer by developing better disease models. Other projects in the laboratory include identifying novel radiosensitizers to take forward into phase 1 clinical trials with parallel co-clinical trials in patient-derived organoids through strong collaborative relationships with colorectal disease management team members and Dr. Paul Romesser, a radiation oncologist. We are seeking candidates with a strong molecular and tumor biology background with experience in cancer biology, along with experience with PDO and PDX animal models. The candidate will have the opportunity to interact with investigators with expertise in the biology of rectal cancer, translational therapeutics, and molecular pathology.

The ideal candidate should have:

• Ph.D. or equivalent in biological science Proficiency with organoids culture, molecular biology, biochemistry, gene expression arrays, DNA, RNA, and protein assays Experience with mouse models will be considered a definite strength At least 3-4 years of experience

Please send CV, bibliography, brief statement of research interests and names of 3 references via email (Including #SmithResearch in the subject line) to: Russell Holmes Surgery Research Lab Manager, SKI HolmesR@mskcc.org MSK is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration without regard to race, color, gender, gender identity or expression, sexual orientation, national origin, age, religion, creed, disability, veteran status or any other factor which cannot lawfully be used as a basis for an employment decision. 

Federal law requires employers to provide reasonable accommodation to qualified individuals with disabilities. Please tell us if you require a reasonable accommodation to apply for a job or to perform your job. Examples of reasonable accommodation include making a change to the application process or work procedures, providing documents in an alternate format, using a sign language interpreter, or using specialized equipment.