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Head of Precision Medicine Technology

Employer
Luxembourg Institute of Health (LIH)
Location
Luxembourg (Localité) (LU)
Salary
to negotiate
Closing date
6 May 2023

View more

Discipline
Health Science, Life Science
Job Type
Manager, Principal Investigator
Employment - Hours
Full time
Duration
Permanent
Qualification
PhD
Sector
Government

Despite extraordinary advances in our understanding of the biology that underlies tumor development and progression and the rapidly evolving field of personalized medicine, cancer is still one of the deadliest diseases. Thanks to the identification of specific actionable mutations, many cancer patients have benefited from the survival improvements observed with targeted therapies. Nevertheless, only a small subset of cancer patients receiving targeted drugs experience an objective response. Because cancer is a complex and heterogeneous disease, the search for effective cancer treatments will in all likelihood need to address not only patient-specific molecular defects but also aspects of the tumor microenvironment. Precision medicine requires treatment to be personalized to the individual patient

Your role…

The Head of Precision Medicine Technology will be in charge of implementing our cancer precision medicine as a scalable routine process via patient-derived 3D culture-based drug profiling platform. Using this platform, the priority goal is to identify personalized treatments for cancer patients.  This entails the following activities :

  • Bring standardized and quality controlled PFP (Personalized Functional Profiling) processes and protocols in all of the participating partner institutions
  • Oversee and align the generation and operational integration of other standardized data sources into a coordinated precision oncology effort
  • Ensure availability of timely, quality controlled data proceed into combinatorial analysis  for the relevant tumor boards at participating partner hospitals
  • Actively engage in start-up activities pertaining to precision medicine in cancer.
  • Provide expert’s input for the LIH research strategy in precision medicine in cancer.  Act as sounding board and provide scientific advice and guidance. 
  • Ensure the proper functioning of the relevant teams : manage the staff, projects portfolio and budget; and adapt technological means and other resources to the needs of the research and technological platform teams.  Contribute actively to fundraising and grant applications.  Provide expert input for the internal and external communication of Precision Medicine projects in cooperation with the LIH communication team.
  • Establish national and international scientific collaboration networks favouring the exchange of competencies

Your Profile…

  • PhD or MD/PhD or equivalent qualification with an excellent track record in drug discovery and chemical compound screening (an industry background would be considered an advantage).
  • At least 10 years of experience in drug screening. Recognized expert in the field.
  • Experience in national and European research projects.
  • Appropriate qualifications or equivalent experience allowing for the supervision of PhD students
  • Active participation in international networks in their field of research.
  • Excellent communication and networking skills allowing for federation of all stakeholders.
  • Extensive management skills as demonstrated by the successful management, for several years, of a large team.
  • Active participation in international networks in the field of oncology.
  • Language skills: perfect command of English, other European languages, especially French and German would be an advantage.

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