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Volume 621 Issue 7980, 28 September 2023

Research intelligence

Whether it is distilling statistics or determining protein structures, the reach of artificial intelligence (AI) is rapidly extending to encompass all aspects of scientific research. Starting this week, Nature takes a deep dive into how AI is helping to reshape the scientific enterprise. In this week’s issue, we look at why researchers are so excited about the burgeoning technology — and we also probe the risks posed by AI-generated disinformation. Over the coming weeks, we will explore other aspects of how AI could transform science, and will bring all of our content together in an online resource.

Cover image: Carlo Cadenas

This Week

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News in Focus

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Books & Arts

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  • News & Views

    • All newborn mammals cry. The neural circuit that stimulates mothers to look after crying offspring has been identified in mice — along with a mechanism that promotes maternal behaviour only after prolonged calls from pups.

      • Flavia Ricciardi
      • Cristina Márquez
      News & Views
    • An organic light-emitting diode has been integrated with an optically driven organic laser to produce laser light from electricity. The design bypasses many of the challenges posed by direct electrical input in such devices.

      • Stéphane Kéna-Cohen
      News & Views
    • Analysis of a 458-million-year-old fossil fish reveals anatomical insights about the vertebrate skull and how skull organization evolved from that of ancestral early vertebrates to that of jawed vertebrates.

      • Zhikun Gai
      • Philip C. J. Donoghue
      News & Views
    • The discovery that the skull has two groups of stem cell that produce similar types of descendant cell has big implications for the field of stem-cell research — and casts light on a developmental disorder that affects many children.

      • Andrei S. Chagin
      • Dana Trompet
      News & Views
  • Reviews

    • Structural studies of amyloid filaments purified from brains of people with neurodegenerative diseases link specific amyloid folds with distinct diseases and provide a basis for the development of models of neurodegenerative disease.

      • Sjors H. W. Scheres
      • Benjamin Ryskeldi-Falcon
      • Michel Goedert
      Review Article
  • Articles

    • This study analyses radio observations of the jet in galaxy M87, from which the existence of a spinning black hole that induces Lense–Thirring precession of a misaligned accretion disk is inferred.

      • Yuzhu Cui
      • Kazuhiro Hada
      • Weiye Zhong
    • Magnetically confined neutral antihydrogen atoms released in a gravity field were found to fall towards Earth like ordinary matter, in accordance with Einstein’s general theory of relativity.

      • E. K. Anderson
      • C. J. Baker
      • J. S. Wurtele
      Article Open Access
    • This study reports the creation of a model thermodynamic engine that is fuelled by the energy difference resulting from changing the statistics of a quantum gas from bosonic to fermionic.

      • Jennifer Koch
      • Keerthy Menon
      • Artur Widera
      Article Open Access
    • In the dipolar XY model, quench dynamics from a polarized initial state lead to spin squeezing that improves with increasing system size, and two refinements show further enhanced squeezing and extended lifetime of the squeezed state by freezing its dynamics.

      • Guillaume Bornet
      • Gabriel Emperauger
      • Antoine Browaeys
    • An electrically driven organic semiconductor laser is achieved by integrating a device structure that efficiently couples an organic light-emitting diode, with extremely high internal-light generation, with a polymer distributed feedback laser.

      • Kou Yoshida
      • Junyi Gong
      • Ifor D. W. Samuel
      Article Open Access
    • Irradiation of chiral Al-salen complexes with violet light demonstrates efficient deracemization of cyclopropanes, enabling reactivity and enantioselectivity to be regulated simultaneously, negating the requirement for tailored catalyst–substrate recognition motifs.

      • Carina Onneken
      • Tobias Morack
      • Ryan Gilmour
      Article Open Access
    • Quantification of climate warming in California using machine learning shows increased daily wildfire growth risk by 25%, with an expected increase of 59% and 172% in 2100, for low- and very-high-emissions scenarios, respectively.

      • Patrick T. Brown
      • Holt Hanley
      • Craig B. Clements
    • Analysis of seismic waves caused by explosions in northern Ukraine recorded by a local network in 2022 demonstrated the ability to automatically identify individual attacks during the Russia–Ukraine conflict in close to real time.

      • Ben D. E. Dando
      • Bettina P. Goertz-Allmann
      • Alexander Liashchuk
      Article Open Access
    • Analysis combining multiple global tree databases reveals that whether a location is invaded by non-native tree species depends on anthropogenic factors, but the severity of the invasion depends on the native species diversity.

      • Camille S. Delavaux
      • Thomas W. Crowther
      • Daniel S. Maynard
      Article Open Access
    • Computed tomography reveals that the cranial anatomy of Ordovician stem-group gnathostome Eriptychius americanus from the Harding Sandstone of Colorado, USA, is distinct among vertebrates.

      • Richard P. Dearden
      • Agnese Lanzetti
      • Ivan J. Sansom
      Article Open Access
    • Experiments in mice identify a neural circuit that relays information about infant cries from the maternal auditory thalamus to hypothalamic oxytocin neurons to induce the release of oxytocin and modulate maternal behaviour.

      • Silvana Valtcheva
      • Habon A. Issa
      • Robert C. Froemke
    • In bats engaged in spontaneous collective spatial behaviour, a robust spatial structure emerges at the group level whereby behaviour is anchored to specific locations, movement patterns and individual social preferences, and many hippocampal neurons are tuned to key features of group dynamics.

      • Angelo Forli
      • Michael M. Yartsev
      Article Open Access
    • The calvarial stem cell niche is populated by a cathepsin K-expressing cell lineage and a newly identified discoidin domain-containing receptor 2-expressing lineage, both of which are required for proper calvarial mineralization.

      • Seoyeon Bok
      • Alisha R. Yallowitz
      • Matthew B. Greenblatt
    • Single-cell transcriptomics and in vivo challenge models establish a key role for the aryl hydrocarbon receptor in regulating the function of enteric endothelial cells in response to environmental cues.

      • Benjamin G. Wiggins
      • Yi-Fang Wang
      • Chris Schiering
      Article Open Access
    • A CRISPR–Cas9 screen in a tumour mouse model identifies CD300ld as a tumour receptor on polymorphonuclear myeloid-derived suppressor cells and in vivo experiments indicate that it is a promising target for cancer immunotherapy.

      • Chaoxiong Wang
      • Xichen Zheng
      • Min Luo
    • Phosphoantigen-mediated BTN2A1 association drives BTN3A1 intracellular fluctuations outwards in a thermodynamically favourable manner, thereby enabling BTN3A1 to push off from the BTN2A1 ectodomain to initiate T cell receptor–mediated γδ T cell activation.

      • Linjie Yuan
      • Xianqiang Ma
      • Yonghui Zhang
      Article Open Access
    • Conditional genetic ferret models enable ionocyte lineage tracing, ionocyte ablation and ionocyte-specific deletion of CFTR to elucidate the roles of pulmonary ionocyte biology and function during human health and disease.

      • Feng Yuan
      • Grace N. Gasser
      • John F. Engelhardt
      Article Open Access
    • Calcium-permeable GluA1 AMPA glutamate receptors are structurally and functionally distinct from the prototypical GluA2-containing AMPA receptors, impacting their role in signal transmission, synaptic plasticity and learning.

      • Danyang Zhang
      • Josip Ivica
      • Ingo H. Greger
      Article Open Access
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Amendments & Corrections

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  • When most researchers leave academia, they don’t plan to return.

    Career Guide
  • Every parent fears the onset of the cold-like symptoms caused by the common respiratory syncytial virus (RSV).

    Nature Outlook
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